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Lack of mpox transmission in a long-term-care facility despite widespread exposure - Kentucky, 2023.

Am J Infect Control

January 2025

Kentucky Department for Public Health, 275 E. Main St. Frankfort, Kentucky, USA, 40601. Electronic address:

A certified nursing assistant (CNA) at a long-term care-facility (LTCF) worked 3 shifts while infectious with monkeypox virus providing direct care to most or all 56 LTCF residents. Despite exposures and a delay of 16 days from symptom onset to diagnosis and public health notification, there is no evidence that transmission occurred. We describe details of this healthcare-associated exposure, public health response, situational risk factors for transmission, and discuss factors that might have contributed to the lack of transmission.

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Using machine learning to forecast peak health care service demand in real-time during the 2022-23 winter season: A pilot in England, UK.

PLoS One

January 2025

Real-time Syndromic Surveillance Team, Field Services, Health Protection Operations, UK Health Security Agency, Birmingham, United Kingdom.

During winter months, there is increased pressure on health care systems in temperature climates due to seasonal increases in respiratory illnesses. Providing real-time short-term forecasts of the demand for health care services helps managers plan their services. During the Winter of 2022-23 we piloted a new forecasting pipeline, using existing surveillance indicators which are sensitive to increases in respiratory syncytial virus (RSV).

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Correlation Between Inflammatory Markers and Pathogenic Bacteria in Children's Winter Respiratory Infections in Xinjiang.

Int J Gen Med

January 2025

Department of Respiratory and Critical Care Medical Department Infectious Diseases Ward, The Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China.

Background: This study examines the distribution characteristics of pathogenic bacteria in respiratory infections and their relationship with inflammatory markers to guide clinical drug use.

Methods: We selected 120 patients with lower respiratory tract infection in the electronic medical record system of Xinjiang Provincial People's Hospital from March 2019 to March 2023 for a case-control study. Using Indirect Immunofluorescence Antibody test(IFA), blood routine, C-reactive Protein (CRP), and High-sensitivity C-reactive Protein(hsCRP), we detected nine respiratory pathogens (Respiratory syncytial virus; Influenza A virus; Influenza B virus; Parainfluenza virus; Adenovirus; Mycoplasma pneumoniae; Chlamydia pneumoniae; Legionella pneumophila type 1; Rickettsia Q) in all patients and analyzed their distribution and correlation.

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Although human metapneumovirus(hMPV) infection can induce severe symptoms in older adults or immunocompromised patients, it usually causes mild symptoms in young immunocompetent adults. The prevalence of hMPV infectious disease is highest during the late winter and early summer. We report a hypoxemic case of hMPV infection in a young immunocompetent man that occurred in the first autumn after the reclassification of coronavirus disease (COVID-19) from Class 2 to Class 5.

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Wheat viruses are major yield-reducing factors, with mixed infections causing substantial economic losses. Determining field virus populations is crucial for effective management and developing virus-resistant cultivars. This study utilized the high-throughput Oxford Nanopore sequencing technique (ONT) to characterize wheat viral populations in major wheat-growing counties of Kansas from 2019 to 2021.

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