Retrieval-augmented generation (RAG) involves a solution by retrieving knowledge from an established database to enhance the performance of large language models (LLM). , these models retrieve information at the sentence or paragraph level, potentially introducing noise and affecting the generation quality. To address these issues, we propose a novel BiomedRAG framework that directly feeds automatically retrieved chunk-based documents into the LLM. Our evaluation of BiomedRAG across four biomedical natural language processing tasks using eight datasets demonstrates that our proposed framework not only improves the performance by 9.95% on average, but also achieves state-of-the-art results, surpassing various baselines by 4.97%. BiomedRAG paves the way for more accurate and adaptable LLM applications in the biomedical domain.
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http://dx.doi.org/10.1016/j.jbi.2024.104769 | DOI Listing |
Well-designed effective interventions promoting sustainable diets are urgently needed to benefit both human and planetary health. This study evaluated the feasibility, acceptability, and potential impact of a pilot blended digital intervention aimed at promoting sustainable diets. We conducted a series of ABA n-of-1 trials with baseline, intervention, and follow-up phases over the course of a year, involving twelve participants.
View Article and Find Full Text PDFTrends Cancer
January 2025
Else Kroener Fresenius Center for Digital Health, Medical Faculty Carl Gustav Carus, Dresden University of Technology (TUD), Dresden, Germany; Department of Medicine I, University Hospital Dresden, Dresden, Germany; Medical Oncology, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, Heidelberg, Germany. Electronic address:
The development of new therapeutic strategies such as immune checkpoint inhibitors (ICIs) and targeted therapies has increased the complexity of the treatment landscape for solid tumors. At the current rate of annual FDA approvals, the potential treatment options could increase by tenfold over the next 5 years. The cost of personalized medicine technologies limits its accessibility, thus increasing socioeconomic disparities in the treated population.
View Article and Find Full Text PDFJ Voice
January 2025
Department of Statistics, Purdue University, Mathematical Sciences Building, 150 N. University Street, Room 231, West Lafayette, IN 47907.
Background: Methods to elicit the vital capacity (VC) include forced vital capacity (FVC) and slow vital capacity (SVC). Because the FVC maneuver can be affected by air trapping or inefficiencies in lung emptying vs. the SVC, the SVC-FVC difference may be substantial and diagnostically meaningful in elderly individuals and patients with respiratory obstruction.
View Article and Find Full Text PDFJ Clin Rheumatol
January 2025
From the Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA.
Introduction: Large language models (LLMs) such as ChatGPT can potentially transform the delivery of health information. This study aims to evaluate the accuracy and completeness of ChatGPT in responding to questions on recombinant zoster vaccination (RZV) in patients with rheumatic and musculoskeletal diseases.
Methods: A cross-sectional study was conducted using 20 prompts based on information from the Centers for Disease Control and Prevention (CDC), the Advisory Committee on Immunization Practices (ACIP), and the American College of Rheumatology (ACR).
J Clin Epidemiol
January 2025
Australian Living Evidence Collaboration, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Background: Living guidelines contain continually updated, and potentially changing, clinical recommendations. The implications of living guidelines for consumers (e.g.
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