Background Context: Stiffness-related functional disability (SRFD) is a well-known complication after long-segment fusion surgery. However, SRFD following decompression with short-segment fusion (1 or 2 levels) compared with decompression alone surgery in the lower lumbar region, which accounts for a significant portion of lumbar range of motion, is poorly documented.
Purpose: This study aimed to compare SRFD after decompression alone (D-A) surgery and decompression with short-segment fusion (D+F) surgery in the lower lumbar region.
Study Design/setting: Retrospective observational study.
Patient Sample: Patients who underwent D-A or D+F surgery at the lower lumbar region (L4 to S1) between 2016 and 2022, with a follow-up period of over 2 years, were reviewed.
Outcome Measure: The visual analog scale (VAS) for the back and leg, Oswestry disability index (ODI), specific functional disability index (SFDI) for SRFD, and lumbar range of motion (LROM) were evaluated as clinical and radiological outcomes preoperatively and at 1 and 2 years postoperatively.
Methods: We divided the lower lumbar region into three segments: L4-5, L5-S1, and L4-5-S1. Out Of the initial 425 patients, 32 pairs in the L4-5 segment, 36 pairs in the L5-S1 segment, and 27 pairs in the L4-5-S1 segment were included in the final cohort after conducting propensity score matching (1:1). Outcomes were compared between the two groups within each segment.
Results: The mean follow-up periods were 27.2, 26.1, and 26.5 months in each group, respectively. In L4-5, there was no difference in the VAS scores for leg pain, ODI, SFDI, and LROM. However, the VAS for back pain was significantly higher in the D+F group preoperatively and at 2 years postoperatively (6.4±2.0 vs. 3.6±2.3, p=.001; 3.6±2.7 vs. 2.1±1.9, p=.046). In the L5-S1, VAS for back pain was significantly higher in the D+F group preoperatively and at 2 years postoperatively (6.2±2.0 vs. 4.4±1.9, p=.001; 4.2±1.7 vs. 3.5±1.3, p=.034). The LROM was significantly lower in the D+F group at 1- and 2-year postoperatively (33.3±8.0° vs. 38.4±9.2°, p=.015; 32.4±7.3° vs. 36.8±9.4°, p=.032). However, the SFDI was higher in the D+F group only at 1 year postoperatively (22.4±7.7 vs. 19.2±5.2, p=.037). In the L4-5-S1, SFDI was significantly higher in the D+F group at 1- and 2-year postoperatively (1 yr: 22.7±7.7 vs. 17.1±7.9, p=.011; 2 yrs: 22.3±7.6 vs. 17.9±7.2, p=.001), LROM was significantly lower in the D+F group (1 yr: 24.1±8.3° vs. 37.0±8.4°, p=.001; 2 yrs: 25.0±6.9° vs. 38.2±6.4°, p=.001).
Conclusion: For the L4-5 segment, there were no differences in LROM and SFDI between the D-A and D+F groups. At L5-S1, significant differences were noted in both parameters at 1-year postoperatively, but SFDI showed no significant differences by the 2-year mark, despite differences in LROM. For two-level fusion at L4-5-S1, significant differences in both LROM and SFDI persisted 2 years postoperatively.
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http://dx.doi.org/10.1016/j.spinee.2024.12.036 | DOI Listing |
BMJ Open
July 2019
Colorectal Surgery, Addenbrooke's Hospital, Cambridge, Cambridgeshire, UK.
Objective: The aim of this study was to assess the nutritional status of patients presenting with small bowel obstruction (SBO), along with associated nutritional interventions and clinical outcomes.
Design: Prospective cohort study.
Setting: 131 UK hospitals with acute surgical services.
Laser Ther
December 2018
Laboratory of Biomaterials and Tissue Engineering, Department of Biosciences, Federal University of Sao Paulo (UNIFESP).
Background And Aims: Bioglass (BG) and Magnesium (Mg) composites have been used for bone tissue engineering proposes due to its osteogenic activity and increased mechanical properties respectively. The introduction of Collagen (Col) is a common and efficient approach for bone tissue engineering applications toward cell proliferation. Recently, studies demonstrated that BG/Col/Mg composites presented proper mechanical properties and were non-cytotoxic.
View Article and Find Full Text PDFBMJ Open
April 2018
Department of Medicine, Imperial College London, London, UK.
Objectives: To describe the characteristics of children and adults with incident type 1 diabetes in contemporary, multiethnic UK, focusing on differences between the islet autoantibody negative and positive.
Design: Observational cohort study.
Setting: 146 mainly secondary care centres across England and Wales.
Clin Infect Dis
April 2018
Infectious Diseases Service, Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Spain.
Intravenous thrombolysis is contraindicated in acute ischemic stroke secondary to infective endocarditis. We report our initial experience in 6 cases of proximal vessel occlusion treated with mechanical thrombectomy, which was safe (no bleeding) and effective (significant early neurological improvement) and might be useful in this clinical setting.
View Article and Find Full Text PDFOccup Environ Med
June 2016
Department of Work Environment, University of Massachusetts Lowell, Lowell, Massachusetts, USA.
Background: Chronic heat stress and dehydration from strenuous work in hot environments is considered an essential component of the epidemic of chronic kidney disease in Central America.
Objective: (1) To assess feasibility of providing an intervention modelled on OSHA's Water.Rest.
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