Immune activation during sustained stress typically worsens stress-related psychopathology. Whether it can enhance stress resilience remains unclear. In this issue of Immunity, Xia, Lu, Lan et al. uncover an anxiolytic function of intestinal IL-22 pathway, which protects against psychological stress.
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http://dx.doi.org/10.1016/j.immuni.2024.11.022 | DOI Listing |
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