Background: Hereditary gingival fibromatosis (HGF) is one of the categories of non-plaque-induced gingival diseases of genetic origin. Current studies show high genetic heterogeneity and suggest that not all forms of HGF are the same and that more than one biological mechanism may result in gingival growth. This report presents a case of syndromic HGF with generalized and complex clinical manifestations associated with other conditions such as body hypertrichosis and hearing deficit.

Methods: This is a case report of a male patient with HGF, detailing the orthodontic and periodontal management that began at the age of 8 and was completed by 21.

Results And Conclusions: The results of this case report demonstrated the importance of early diagnosis and the establishment of a correct treatment plan that provided, in the long-term, highly positive effects, minimizing impacts affecting the oral health-related quality of life of individuals with HGF.

Key Points: This is a case report of a male patient with HGF, detailing the orthodontic and periodontal management that began at age 8 and was completed by age 21. Clinical, genetic, and histological data are reported over the 13 years of follow-up. Due to the numerous complications caused by HGF, early diagnosis and the establishment of an appropriate treatment plan are imperative.

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http://dx.doi.org/10.1002/cap.10331DOI Listing

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