This article highlights some advances in visceral surgery in 2024. In the hepato-pancreato-biliary field, liquid biopsies, immunotherapy, and robotics have revolutionized diagnosis and treatment, while artificial intelligence could enhance planning and operational safety. In endocrine surgery, a more conservative approach is recommended for well-differentiated thyroid cancers. In colorectal surgery, intracorporeal anastomosis reduces the risk of postoperative hernia, with benefits in functional recovery through reduced postoperative ileus. Finally, in esogastric surgery, gastropexy without fundoplication is an alternative for fragile patients, minimizing risks while maintaining good quality of life.
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| http://dx.doi.org/10.53738/REVMED.2025.21.900-1.17 | DOI Listing |
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[Visceral surgery : what's new in 2024].
Rev Med Suisse
January 2025
Service de chirurgie viscérale, Département de chirurgie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
This article highlights some advances in visceral surgery in 2024. In the hepato-pancreato-biliary field, liquid biopsies, immunotherapy, and robotics have revolutionized diagnosis and treatment, while artificial intelligence could enhance planning and operational safety. In endocrine surgery, a more conservative approach is recommended for well-differentiated thyroid cancers.
View Article and Find Full Text PDFUltrasonic emulsification and aspiration for coral reef atherosclerosis as a novel alternative to transaortic endarterectomy and thoracic aorta-based bypass grafting.
J Vasc Surg Cases Innov Tech
April 2025
Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Case Western Reserve University School of Medicine, University Hospitals Harrington Heart and Vascular Institute, Cleveland, OH.
Transaortic endarterectomy (TE) is an effective and durable method of restoring patency in the aorta afflicted with atherosclerotic disease, which most commonly affects the infrarenal aorta and common iliac artery. When the suprarenal aorta is involved, the disease is usually confined to the orifices of the visceral vessels without obstruction of the aortic lumen. In rare cases, dense, calcified, exophytic, and amorphous lesions causing severe luminal obstruction, termed coral reef atherosclerosis (CRA) of the suprarenal aorta, may occur.
View Article and Find Full Text PDFGene expression dynamics in fibroblasts during early-stage murine pancreatic carcinogenesis.
iScience
January 2025
Department of Visceral, Vascular and Endocrine Surgery, Martin-Luther-University Halle-Wittenberg, University Medical Center Halle, 06120 Halle (Saale), Germany.
Pancreatic ductal adenocarcinoma (PDAC) is characterized by aggressive growth and metastasis, partly driven by fibroblast-mediated stromal interactions. Using RNA sequencing of fibroblasts from early-stage KPC mouse models, we identified significant upregulation of genes involved in adipogenesis, fatty acid metabolism, and the ROS pathway. ANGPTL4, a key adipogenesis regulator, was highly expressed in fibroblasts and promoted pancreatic cancer cell proliferation and migration through paracrine signaling.
View Article and Find Full Text PDFVersatility of the Anterolateral Thigh Flap for Abdominal Wall Reconstruction.
Plast Reconstr Surg Glob Open
January 2025
From the Department of Plastic Surgery and Hand Surgery, Cantonal Hospital Aarau, Aarau, Switzerland.
Background: Abdominal wall reconstruction represents an ambitious and demanding challenge. This study aimed to illustrate the versatility of the anterolateral thigh (ALT) flap in its different designs for the reconstruction of complex defects of the abdominal wall.
Methods: Charts of patients with complex abdominal wall defects who underwent a reconstruction with an ALT flap at the University Hospital of Zurich (2018-2020) were reviewed retrospectively.
Achieving room air quality of room class Ib in the aseptic area using a mobile sterile ventilation unit in a room class II surgical unit.
GMS Hyg Infect Control
December 2024
Institute of Hygiene and Environmental Medicine, University Medicine Greifswald, Germany.
Introduction: Room air class (RC) Ib may be necessary for surgical procedures in aseptic working areas. The aim of the study was to examine whether a mobile, three-stage sterile ventilation unit (MSVU) can replace a room ventilation system (RVS) with turbulent mixed flow (TMF) in the area of the operating field and on the instrument table from hygienic-microbiological point of view.
Method: During 26 surgeries (varicose vein stripping or treatment of umbilical and inguinal hernias), the microbial load was recorded at 4 measuring points (M1-M4) during regular operations by setting up sedimentation plates and measuring the particle concentration.
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