Chorioangiomas are benign vascular tumors of the placenta originating from chorionic tissue. They are also known as hemangiomas of the placenta. They occur in approximately 0.5%-1% of all pregnancies. Large chorioangiomas are rare and may lead to serious fetal and maternal complications. Here, we are describing a case of giant placental chorioangioma in a 19-year-old young female (G2A1) who presented to us at 39 weeks of gestation with decreased fetal movements. Ultrasound examination revealed an enlarged placenta with a well-defined 9.4 cm × 9.3 cm heteroechoic area with increased vascularity. Cesarean section was performed in view of fetal distress and a female baby weighing 1.6 kg was delivered. The newborn died within 2 weeks due to pulmonary hypoplasia and hemodynamic failure. The diagnosis of chorioangioma was confirmed with histopathology. This case depicts the necessity of early diagnosis, close fetal monitoring, and timely intervention in achieving a favorable pregnancy outcome.
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http://dx.doi.org/10.4103/jmau.jmau_71_22 | DOI Listing |
J Microsc Ultrastruct
January 2023
Department of Pathology, UCMS and GTB Hospital, New Delhi, India.
Chorioangiomas are benign vascular tumors of the placenta originating from chorionic tissue. They are also known as hemangiomas of the placenta. They occur in approximately 0.
View Article and Find Full Text PDFSci Rep
December 2024
Laboratory of Molecular and Cellular Immunology, Institute of Molecular Biology NAS RA, 7 Hasratyan Str., Yerevan, 0014, Armenia.
Antiphospholipid syndrome (APS) is associated with recurrent pregnancy morbidity, yet the underlying mechanisms remain elusive. We performed multifaceted characterization of the biological and transcriptomic signatures of mouse placenta and uterine natural killer (uNK) cells in APS. Histological analysis of APS placentas unveiled placental abnormalities, including disturbed angiogenesis, occasional necrotic areas, fibrin deposition, and nucleated red blood cell enrichment.
View Article and Find Full Text PDFJ Obstet Gynaecol Res
January 2025
Department of Environmental Health, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Anat Rec (Hoboken)
November 2024
Institut des Sciences de l'Evolution de Montpellier (ISEM), University of Montpellier, CNRS, IRD, Montpellier, France.
The length of the snout in mammals has important evolutionary consequences for the functional systems housed within the rostrum. However, whether increased snout lengths lead to expanded olfactory performance has rarely been examined. Here, we investigate inner rostral function among 10 species of myrmecophagous (ant- and/or termite-eating) placental mammals and 10 closely related species.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
November 2024
Department of Biomedical Sciences. University of Missouri, Columbia, MO 65211.
Pregnant women are often prescribed or abuse opioid drugs. The placenta is likely the key to understanding how opioids cause adverse pregnancy outcomes. Maternal oxycodone (OXY) exposure of pregnant mice leads to disturbances in the layer of invasive parietal trophoblast giant cells (pTGC) that forms the interface between the placenta and uterus.
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