Lapsi ( (Roxb.) B.L.Burtt & A.W.Hill) is an useful medicinal plant known for various bioactive compounds and diverse biological activities. The aim of this article was to comprehensively review the available information about the traditional uses, chemical constituents and biological activities of Lapsi. A comprehensive literature search was conducted using various databases, including PubMed, Scopus, Web of Science, Google Scholar, and ScienceDirect. Fruits, leaves, and bark have been extensively studied for their potential health benefits, owing to the presence of various phytochemicals such as polyphenols including flavonoids and phenolic acids, terpenoids, and essential oils. These compounds exhibited antioxidant, antimicrobial, anti-inflammatory, and anticancer properties. Additionally, the nutritional value of Lapsi fruit contributes to its popularity as a food source in traditional cuisines. In conclusion, this review explores the chemical constituents and pharmacological activities of Lapsi and highlights its importance as a multipurpose plant in various fields.
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http://dx.doi.org/10.1016/j.heliyon.2024.e41146 | DOI Listing |
Heliyon
January 2025
Pharmacy Program, Gandaki University, Pokhara, 33700, Nepal.
Lapsi ( (Roxb.) B.L.
View Article and Find Full Text PDFAim Of The Study: This study investigated the mechanism by which the Postoperative Tongqi Formula (PTQF) treats postoperative ileus (POI) through regulation of the p38 MAPK signaling pathway, Zona occludens 1 (ZO-1) protein, and metabolism.
Methods: The primary components of PTQF were characterized using UHPLC-Q-TOF-MS/MS. The identified compounds subsequently employed network pharmacology to predict the signaling pathways associated with the inflammatory phase of POI.
Mini Rev Med Chem
January 2025
Department of Chemistry, Abdul Wali Khan University, Mardan, 23200, Pakistan.
Organic compounds containing azines, di-imines, or bis-Schiff-bases have two azomethine (-CH=N-) functional groups associated with a bridging component. These constituents have attracted attention from a diversity of disciplines, comprising coordination, medicinal, agriculture chemistry, and organic synthesis, because of their comprehensive chemical reactivity and nature. This study determines common synthetic approaches and various biological and pharmacological activities of several substituted bis-Schiff byproducts.
View Article and Find Full Text PDFPhytochem Anal
January 2025
College of Pharmacy, Anhui University of Chinese Medicine, Hefei, China.
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease that primarily manifests with symptoms such as heat and toxin. However, the key components and molecular mechanisms of Zhizi Baipi decoction (ZBD) in the treatment of RA are still unclear.
Objectives: The study aimed to explore the mechanism of action of ZBD for treating RA through ingredient analysis, network pharmacology, and experimental validation.
Phytochem Anal
January 2025
School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China.
Introduction: Farfarae Flos is widely used as a traditional herbal medicine. Currently, its size has been the primary grading criterion used in market circulation. Whether this empirical criterion can accurately reflect the quality of the medicinal material has not been systematically studied.
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