This Patent Highlight explores recent innovations in neuroscience and neurotechnology, particularly in brain monitoring and stimulation. It examines four essential patents: novel psychoplastogens for neuronal growth, techniques for transferring emotional states, and advanced systems for self-guided neural diagnostics and treatment. The discussion extends to deep brain stimulation (DBS) for motor and memory disorders, enhanced brain function monitoring through electroencephalography (EEG), and the role of artificial intelligence in personalizing treatment strategies. These advancements represent a pivotal development in neurotechnology, introducing innovative methodologies for elucidating neurological mechanisms, addressing psychiatric disorders, and augmenting cognitive and neural function.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726356 | PMC |
http://dx.doi.org/10.1021/acsmedchemlett.4c00584 | DOI Listing |
Introduction: This study aimed to identify cognitive tests that optimally relate to tau positron emission tomography (PET) signal in the inferior temporal cortex (ITC), a neocortical region associated with early tau accumulation in Alzheimer's disease (AD).
Methods: We analyzed cross-sectional data from the harvard aging brain study (HABS) (= 128) and the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study (= 393). We used elastic net regression to identify the most robust cognitive correlates of tau PET signal in the ITC.
Heliyon
January 2025
School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Bevacizumab is widely used in various clinical indications, but investigations into its optimal dosage for treating CNS metastases remain limited. The BEEP regimen, comprising bevacizumab, etoposide, and cisplatin, has recently demonstrated promising clinical outcomes for patients with breast cancer brain metastasis (BCBM) or leptomeningeal metastasis (LM). This study aimed to evaluate the exposure-response relationship of bevacizumab in BCBM patients and to explore the improved CNS penetration of chemotherapy by bevacizumab with LM patients.
View Article and Find Full Text PDFACS Med Chem Lett
January 2025
Usona Institute, Fitchburg, Wisconsin 53711-5300, United States.
This Patent Highlight explores recent innovations in neuroscience and neurotechnology, particularly in brain monitoring and stimulation. It examines four essential patents: novel psychoplastogens for neuronal growth, techniques for transferring emotional states, and advanced systems for self-guided neural diagnostics and treatment. The discussion extends to deep brain stimulation (DBS) for motor and memory disorders, enhanced brain function monitoring through electroencephalography (EEG), and the role of artificial intelligence in personalizing treatment strategies.
View Article and Find Full Text PDFNurs Crit Care
January 2025
Intensive Care Unit, Affiliated Hospital of Jining Medical University, Jining, China.
Background: Patients discharged from the intensive care unit (ICU) can experience post-intensive care syndrome (PICS), which is comprised of cognitive, physical and psychological impairments.
Aim: The objective of this study was to identify the prevalence of and risk factors associated with all three domains of PICS at the first and third month after ICU discharge.
Design: A prospective descriptive-analytic study was conducted in two ICUs of a Chinese university hospital.
J Clin Neurophysiol
January 2025
Service de Neurologie, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles, Bruxelles, Belgique; and.
Purpose: The American Clinical Neurophysiology Society has provided a set of recommendations on the use of critical care EEG monitoring (CEEG). However, these recommendations have not been prospectively validated. We aimed to assess the adherence to the American Clinical Neurophysiology Society recommendations for obtaining CEEG for different indications and the yield of obtained CEEG according to these different indications.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!