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Monocytes generated by interleukin-6-treated human hematopoietic stem and progenitor cells secrete calprotectin that inhibits erythropoiesis.
iScience
January 2025
INSERM U1287, Université Paris-Saclay, Gustave Roussy Cancer Center, Villejuif, France.
Elevated circulating levels of calprotectin (CAL), the S100A8/A9 heterodimer, are biomarkers of severe systemic inflammation. Here, we investigate the effects of CAL on early human hematopoiesis. CAL demonstrates limited impact on gene expression in stem and progenitor cells, in contrast with interleukin-6 (IL6), which promotes the expression of the and genes in hematopoietic progenitors and the generation of monocytes that release CAL.
View Article and Find Full Text PDFPrevalence of body image dissatisfaction and associated factors among high school adolescent in Hawassa city, Ethiopia.
Heliyon
January 2025
School of Nursing, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.
Background: Adolescence is a period in which individuals are more concerned with their body image. However, little is known about the prevalence of body image dissatisfaction and its associated factors. Thus, this study aimed to assess the prevalence of body image dissatisfaction and associated factors among high school adolescents in Hawassa city in 2023.
View Article and Find Full Text PDFImproved Diet Quality in Elite and Entry-Level Military Women Compared With Civilian-Matched Counterparts.
Curr Dev Nutr
January 2025
United States Army Research Institute of Environmental Medicine (USARIEM), Military Performance Division, Natick, MA, United States.
Background: Dietary intake is a modifiable factor linked to short-term and long-term health. The Healthy Eating Index (HEI) is an objective measure to assess diet quality and population-level comparisons, like military to civilian.
Objectives: This study aimed to characterize diet quality of early-career and mid-career female soldiers compared with that of age-matches and sex-matched civilians and to link indicators of cardiometabolic disease risk to dietary outcomes and health status.
Colorectal cancer and microbiota: systematic review.
Prz Gastroenterol
March 2024
Department of General Surgery, Medical Centre of West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
Introduction: The gut microbiome maintains the mucus membrane barrier's integrity, and it is modulated by the host's immune system.
Aim: To detect the effect of microbiota modulation using probiotics, prebiotics, symbiotics, and natural changes on colorectal cancers (CRCs).
Methods: A PubMed search was conducted to retrieve the original and articles published in English language from 2010 until 2021 containing the following keywords: 1) CRCs, 2) CRCs treatment (i.
Promoting healthy digital device usage: recommendations for youth and parents.
World Psychiatry
February 2025
Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
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