Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41569-025-01122-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A reduction-secretion system contributes to roxarsone (V) degradation and efflux in Brevundimonas sp. M20.
BMC Microbiol
January 2025
School of Laboratory Animal & Shandong Laboratory Animal Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Ji'nan, Shandong, 250117, China.
Roxarsone (V) (Rox(V)) is an organoarsenical compound that poses significant risks to aquatic ecosystems and various diseases. Reducing trivalent 3-amino-4-hydroxyphenylarsonic acid (HAPA(III)) offers a competitive advantage; however, it leads to localized arsenic contamination, which can disrupt the soil microbiome and impede plant growth. Three genes, BsntrA, arsC2, and BsexpA, encoding nitroreductase, arsenate reductase, and MFS transporter, respectively, were identified in the Rox(V)-resistant strain Brevundimonas sp.
View Article and Find Full Text PDFEngineering extracellular vesicles for therapeutic delivery in ischaemic stroke.
Nat Rev Cardiol
January 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Intelligent in-cell electrophysiology: Reconstructing intracellular action potentials using a physics-informed deep learning model trained on nanoelectrode array recordings.
Nat Commun
January 2025
Aiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.
Intracellular electrophysiology is essential in neuroscience, cardiology, and pharmacology for studying cells' electrical properties. Traditional methods like patch-clamp are precise but low-throughput and invasive. Nanoelectrode Arrays (NEAs) offer a promising alternative by enabling simultaneous intracellular and extracellular action potential (iAP and eAP) recordings with high throughput.
View Article and Find Full Text PDFThe pericellular function of Fibulin-7 in the adhesion of oligodendrocyte lineage cells to neuronal axons during CNS myelination.
Biochem Biophys Res Commun
January 2025
Department of Molecular and Cellular Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan; Department of Clinical Bioanalysis and Molecular Biology, Graduate School of Medical and Dental Sciences, Institute Science of Tokyo/TMDU, Tokyo, Japan. Electronic address:
Myelin is an electrical insulator that enables saltatory nerve conduction and is essential for proper functioning of the central nervous system (CNS). It is formed by oligodendrocytes (OLs) in the CNS, and during OL development various molecules, including extracellular matrix (ECM) proteins, regulate OL differentiation and myelination; however, the role of ECM proteins in these processes is not well understood. Our present work is centered on the analyses of the expression and function of fibulin-7 (Fbln7), an ECM protein of the fibulin family, in OL differentiation.
View Article and Find Full Text PDFAECuration: Automated event curation for spike sorting.
J Neural Eng
January 2025
Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, Pennsylvania, 15213, UNITED STATES.
Spike sorting is a commonly used analysis method for identifying single-units and multi-units from extracellular recordings. The extracellular recordings contain a mixture of signal components, such as neural and non-neural events, possibly due to motion and breathing artifacts or electrical interference. Identifying single and multi-unit spikes using a simple threshold-crossing method may lead to uncertainty in differentiating the actual neural spikes from non-neural spikes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!