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http://dx.doi.org/10.1038/d41586-025-00055-w | DOI Listing |
Exp Cell Res
January 2025
School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, UK. Electronic address:
On June 30, 2020, Professor Joseph Grafton Gall announced his retirement at 92. On August 13, 2020, Joe's former trainees and colleagues held a retirement celebration online to celebrate Joe's "Remarkable Career with Astonishing Discoveries", covering Joe's nearly 70 years of education and research. As a representative of Joe's trainees in the 2000s, I gave a speech titled "Seven Theorems of Joe".
View Article and Find Full Text PDFAquat Toxicol
May 2024
School of Public Health, Chongqing Medical University, Chongqing 400016, China. Electronic address:
This review explains the sources of nanoplastics (NPs) and microplastics (MPs), their release, fate, and associated health risks in the aquatic environment. In the 21st century, scientists are grappling with a major challenge posed by MPs and NPs. The global production of plastic has skyrocketed from 1.
View Article and Find Full Text PDFNature
February 2024
Department of Genome Sciences, University of Washington, Seattle, WA, USA.
The house mouse (Mus musculus) is an exceptional model system, combining genetic tractability with close evolutionary affinity to humans. Mouse gestation lasts only 3 weeks, during which the genome orchestrates the astonishing transformation of a single-cell zygote into a free-living pup composed of more than 500 million cells. Here, to establish a global framework for exploring mammalian development, we applied optimized single-cell combinatorial indexing to profile the transcriptional states of 12.
View Article and Find Full Text PDFbioRxiv
April 2023
Department of Genome Sciences, University of Washington, Seattle, WA, USA.
The house mouse, , is an exceptional model system, combining genetic tractability with close homology to human biology. Gestation in mouse development lasts just under three weeks, a period during which its genome orchestrates the astonishing transformation of a single cell zygote into a free-living pup composed of >500 million cells. Towards a global framework for exploring mammalian development, we applied single cell combinatorial indexing (sci-*) to profile the transcriptional states of 12.
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