Introduction: Sickle cell anemia has a genetic origin characterized by an autosomal recessive inheritance pattern. The nervous system may be subject to vaso-occlusion and, consequently, affect the proper functioning of the central portion of hearing.
Objective: To assess central auditory skills and analyze short- and long-latency auditory evoked potentials in children with sickle cell disease.
Methods: Cross-sectional study. All children had normal hearing thresholds, and their central auditory processing underwent behavioral assessment with a battery of tests involving dichotic and monotic listening, binaural interaction, and temporal processing. The electrophysiological assessment used short- and long-latency auditory evoked potentials. Descriptive statistics were performed.
Results: Of the 28 subjects evaluated (mean age of 9.46 years), 18 were females and 10 were males. Central auditory processing disorder was identified in 85.7% of the children. The auditory skills of figure-ground for verbal sounds, binaural interaction, and complex temporal ordering were the most affected. An increase in the absolute latencies of Waves III and V was observed in the short-latency potential.
Conclusion: Individuals with sickle cell disease have central auditory processing disorder, identified primarily by behavioral assessment.
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http://dx.doi.org/10.1002/pbc.31539 | DOI Listing |
Indian J Otolaryngol Head Neck Surg
January 2025
Department of Audiology, School of Rehabilitation Sciences, Babol University of Medical Sciences, Babol, Iran.
Twins, especially second-born twins, have more unfavorable pregnancy results than singletons. Despite the fact that more than half of twins have been prematurely born, research on auditory brainstem maturation in premature twins is limited. Thus, the goal of this research was to compare the maturation of the maturation of the auditory brainstem in preterm twins and singletons, as well as investigate this maturation process with regard to birth order.
View Article and Find Full Text PDFEar Hear
March 2025
Department of Otorhinolaryngology, Peking Union Medical College Hospital, Beijing, People's Republic of China.
Objectives: Auditory deprivation results in functional enhancement of the remaining intact visual modality, and the underlying mechanisms include cross-modal recruitment of additional resources from the auditory cortex and compensatory reorganization of the visual network in bilateral deafness. However, how resources are allocated between hearing and vision has not been determined in patients with partial auditory deprivation. This study aimed to investigate the relationship between functional plasticity of the visual and auditory pathways in patients with congenital single-sided deafness (SSD), a typical partial deprivation condition.
View Article and Find Full Text PDFNeuropsychiatr Dis Treat
March 2025
Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan.
Objective: The mismatch negativity (MMN) reflects automatic cognitive function in response to auditory stimulation. The MMN to duration deviant (d-MMN) amplitude is known to be lower in children with autism spectrum disorder (ASD) than in healthy controls (HCs). Moreover, the d-MMN is known to be a trait maker of schizophrenia because it is unaffected by the duration of illness.
View Article and Find Full Text PDFProg Neuropsychopharmacol Biol Psychiatry
March 2025
Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nürnberg, Schwabachanlage 6, 91054 Erlangen, Germany; Institute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany. Electronic address:
Fear, whether innate or learned, is an essential emotion required for survival. The learning, and subsequent memory, of fearful events enhances our ability to recognise and respond to threats, aiding adaptation to new, ever-changing environments. Considerable research has leveraged associative learning protocols such as contextual or auditory forms of fear conditioning in rodents, to understand fear learning, memory consolidation and extinction phases of memory.
View Article and Find Full Text PDFJ Neuroeng Rehabil
March 2025
The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Background: This prospective cohort study was designed to investigate and compare the effectiveness of rehabilitation training robots versus conventional rehabilitation training on stroke survivors by monitoring alterations in brain network of stroke patients before and after robot intervention.
Methods: Between September 2020 and November 2021, stroke patients at four grade-A tertiary hospitals underwent limb rehabilitation training. Of the total of participants, 117 patients received conventional limb rehabilitation, 93 patients participated in upper-limb robot training, and 103 patients underwent lower-limb robot training.
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