Saturated F-Rings from Alkenes.

Angew Chem Int Ed Engl

Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.

Published: January 2025

A general method to convert simple exocyclic alkenes into saturated F-rings has been developed. The reaction involves reagent CFI(OAc). The reaction efficiently works on the mg-, g-, and even multigram scale.

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Source
http://dx.doi.org/10.1002/anie.202422899DOI Listing

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