Automated Vehicles (AVs) are on the cusp of commercialization, prompting global governments to organize the forthcoming mobility phase. However, the advancement of technology alone cannot guarantee the successful commercialization of AVs without insights into the accidents on the read roads where Human-driven Vehicles (HV) coexist. To address such an issue, The New Car Assessment Program (NCAP) is currently in progress, and scenario-based approaches have been spotlighted. Scenario approaches offer a unique advantage by evaluating AV driving safety through carefully designed scenarios that reflect various real-world situations. While most scenario studies favor the data-driven approach, the studies have several shortcomings, including perspectives of data, AI models, and scenario standards. Hence, we propose a holistic framework for generating functional, logical, and concrete scenarios. The framework composes explainable scenarios (X-Scenarios) based on real-driving LiDAR data, and visual trend interpretation using eXplainable AI (XAI). The framework consists of four components as follows: (1) voxelization of LiDAR PCD and extraction of kinematic features; (2) classification of critical situations and generation of attention maps using visual XAI and Vision Transformer (ViT) to generate range values of elements in logical scenarios; (3) analysis of the importance and correlations among input data features using SHapley Additive exPlanations (SHAP) for selecting scenarios based on the most relevant criteria; and (4) composition of AV safety assessment scenarios. X-scenarios generated from our framework involve the parameters of ego vehicles and surrounding objects on the highways and urban roads. With our framework highly trustworthy AV safety assessment scenarios can be created. This novel work provides an integrated solution to generate trustworthy scenarios for AV safety assessment by explaining the scenario selection process.
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http://dx.doi.org/10.1016/j.aap.2024.107902 | DOI Listing |
Neurosurg Rev
January 2025
Hengyang Key Laboratory of Hemorrhagic Cerebrovascular Disease, Department of Neurosurgery, the Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, 421000, Hunan, China.
Patients with intracranial aneurysms (IA) undergoing endovascular treatment face varying risks and benefits when tirofiban is used for thromboprophylaxis during surgery. Currently, there is a lack of high-level evidence summarizing this information. This study aims to conduct a systematic review and meta-analysis to evaluate the efficacy and safety of tirofiban during endovascular treatment of IA.
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January 2025
Macquarie Medical School, Macquarie University, Sydney, NSW, Australia.
Magnetic resonance imaging (MRI) is frequently used to monitor disease progression in multiple sclerosis (MS). This study aims to systematically evaluate the correlation between MRI measures and histopathological changes, including demyelination, axonal loss, and gliosis, in the central nervous system of MS patients. We systematically reviewed post-mortem histological studies evaluating myelin density, axonal loss, and gliosis using quantitative imaging in MS.
View Article and Find Full Text PDFInt J Behav Med
January 2025
Qilu Hospital of Shandong University, No. 107 Wen Hua Xi Road, Jinan, 250012, Shandong Province, China.
Background: Irritable bowel syndrome (IBS) has been effectively treated with acupuncture, but the significance of quality of life, depression, and anxiety in the assessment of IBS patients has received little consideration. This study examined the impact of acupuncture on depression, anxiety, and quality of life in IBS patients.
Method: PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), EMBASE, China Science and Technology Journal Database (VIP), Chinese Biological Medical (CBM, SinoMed) Database, and the Wan Fang Database were among the electronic databases from which relevant randomized controlled trials (RCTs) were systematically retrieved between their inception and July 2023.
J Relig Health
January 2025
School of Social Work, Hadassah Academic College, Jerusalem, Israel.
Religious informal helpers may play a crucial role in recognizing and providing referrals to mental health professional for at-risk individuals, including those with mental illness, especially since members of religious communities tend to conceal their difficulties and to view religious leaders as a sole source of assistance. This quantitative study aimed to explore Jewish bathhouse attendants ("balaniyot") who assist women in their monthly immersion, a unique situation in which mental health symptoms (e.g.
View Article and Find Full Text PDFAAPS PharmSciTech
January 2025
School of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, New Delhi, India, 110017.
The biopharmaceutical industry has witnessed significant growth in the development and approval of biosimilars. These biosimilars aim to provide cost-effective alternatives to expensive originator biosimilars, alleviating financial pressures within healthcare. The manufacturing of biosimilars is a highly complex process that involves several stages, each of which must meet strict regulatory standards to ensure that the final product is highly similar to the reference biologic.
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