LGBTQ adolescents and young adults have been disproportionately affected by the COVID-19 pandemic. This review aims to describe the impact of the COVID-19 crisis on mental health among LGBTQ adolescents and young adults, identify associated factors, and summarize coping strategies. A systematic review was conducted by searching six databases (PubMed, Embase, PsycINFO, CINAHL, Web of Science, MEDLINE). Eligibility criteria included (1) reported mental health outcomes, (2) conducted among LGBTQ adolescents and young adults, and (3) data collection occurred since January 2020. All studies were screened independently, and relevant data were synthesized following PRISMA guidelines. Of 395 records, 67 articles were screened for eligibility. Among these, 39 studies met the inclusion criteria. LGBTQ adolescents and young adults reported substantial mental health burdens, including depression, anxiety, stress, and loneliness during the pandemic. A pooled prevalence of depressive symptoms with a combined sample size of 7326 LGBTQ adolescents and young adults was 59% (95%CI: 0.48-0.70), (I = 98.95%, p < 0.001). Among anxiety outcomes, the pooled prevalence with a sample size of 3258 LGBTQ adolescents and young adults was 55% (95% CI: 0.46-0.63), (I = 95.70%, p < 0.001). Individual factors associated with mental distress included age, gender, and history of mental health disorders. Interpersonal and community-level factors included loss of safe spaces, family support, and discrimination on sexual and gender minority identity. Strategies to cope with distress include the use of social media and increased use of alcohol, tobacco, and other drugs. The pandemic has had a substantial negative impact on psychological distress among LGBTQ adolescents and young adults. Results substantiate the need for further research into social media as a coping instrument and the expansion of telehealth mental health services.
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http://dx.doi.org/10.1016/j.jpsychires.2024.12.037 | DOI Listing |
Pharmazie
December 2024
Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.
: Major Depressive Disorder (MDD) is a prevalent and debilitating mental disorder that has been linked to hyperhomocysteinemia and folate deficiency. These conditions are influenced by the methylenetetrahydrofolate reductase () gene, which plays a crucial role in converting homocysteine to methionine and is essential for folate metabolism and neurotransmitter synthesis, including serotonin. : This study explored the association between and polymorphisms among Saudi MDD patients attending the Erada Complex for Mental Health and Erada Services outpatient clinic in Jeddah, Saudi Arabia.
View Article and Find Full Text PDFJ Occup Rehabil
January 2025
McWilliams School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Purpose: We aimed to develop an online vocational rehabilitation (VR) readiness screening (VRRS) tool for young adults diagnosed with cancer. VR readiness was defined as being physically and cognitively ready to enter or return to work or school.
Methods: We developed an initial VRRS tool informed by previous studies, a scoping review to determine such a tool had not already been developed, and consultation with subject matter experts.
Behav Res Methods
January 2025
Centre for Cognitive and Brain Sciences and Department of Psychology, University of Macau, Taipa, 999078, Macau, China.
The autobiographical implicit association test (aIAT) is an approach of memory detection that can be used to identify true autobiographical memories. This study incorporates mouse-tracking (MT) into aIAT, which offers a more robust technique of memory detection. Participants were assigned to mock crime and then performed the aIAT with MT.
View Article and Find Full Text PDFActa Neurochir (Wien)
January 2025
Department of Neurosurgery and Department of Neuroscience, Fujian Key Laboratory of Brain Tumors Diagnosis and Precision Treatment, Xiamen Key Laboratory of Brain Center, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Purpose: To investigate the technique for dorsal median sulcus (DMS) mapping and assess its application value in preserving dorsal columnn (DC) function during intramedullary space occupying surgery based on a single-center experience.
Methods: A retrospective analysis was conducted on 41 cases of intramedullary spinal cord tumor admitted to the Department of Neurosurgery at the First Affiliated Hospital of Xiamen University from March 2017 to August 2023. All included cases underwent intraoperative electrophysiological monitoring, and were divided into a study group (n = 18) and a control group (n = 23), based on whether DMS mapping technique was utilized.
Eur J Trauma Emerg Surg
January 2025
Department of Trauma Surgery and Orthopedics, Goethe University, University Hospital, Frankfurt, Germany.
Objective: Global per capita alcohol consumption is increasing, posing significant socioeconomic and medical challenges also due to alcohol-related traumatic injuries but also its biological effects. Trauma as a leading cause of death in young adults, is often associated with an increased risk of complications, such as sepsis and multiple organ failure, due to immunological imbalances. Regulatory T cells play a crucial role in maintaining immune homeostasis by regulating the inflammatory response.
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