A search for light long-lived particles (LLPs) decaying to displaced jets is presented, using a data sample of proton-proton collisions at a center-of-mass energy of 13.6 TeV, corresponding to an integrated luminosity of 34.7 fb, collected with the CMS detector at the CERN LHC in 2022. Novel trigger, reconstruction, and machine-learning techniques were developed for and employed in this search. After all selections, the observations are consistent with the background predictions. Limits are presented on the branching fraction of the Higgs boson to LLPs that subsequently decay to quark pairs or tau lepton pairs. An improvement by up to a factor of 10 is achieved over previous limits for models with LLP masses smaller than 60 GeV and proper decay lengths smaller than 1 m. The first constraints are placed on the fraternal twin Higgs (FTH) and folded supersymmetry (FSUSY) models, where the lower bounds on the top quark partner mass reach up to 350 GeV for the FTH model and 250 GeV for the FSUSY model.
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http://dx.doi.org/10.1088/1361-6633/adaa13 | DOI Listing |
Molecules
February 2025
Department of Pharmaceutical Chemistry, Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu 333053, India.
Increasing cases of sunburn is one of the serious problems across the globe. In this connection, there is an urgent requirement for some effective sun screening agents. In the search for the same, nanoemulsions of some new synthesized and characterized chalcone derivatives were prepared and evaluated in vitro and in vivo.
View Article and Find Full Text PDFBrief Bioinform
March 2025
Division of Microbiology, Tulane National Primate Research Center, Tulane University, Covington, LA 70433, United States.
This work aims to (1) identify microbial and metabolic alterations and (2) reveal a shift in phenylalanine production-consumption equilibrium in individuals with HIV. We conducted extensive searches in multiple databases [MEDLINE, Web of Science (including Cell Press, Oxford, HighWire, Science Direct, IOS Press, Springer Nature, PNAS, and Wiley), Google Scholar, and Embase] and selected two case-control 16S data sets (GenBank IDs: SRP039076 and EBI ID: ERP003611) for analysis. We assessed alpha and beta diversity, performed univariate tests on genus-level relative abundances, and identified significant microbiome features using random forest.
View Article and Find Full Text PDFJ Cosmet Dermatol
March 2025
Dermatology Hospital of Zhejiang Province, Huzhou, Zhejiang, China.
Background: In recent decades, our understanding of the pathogenesis and pathophysiology of skin photoaging has improved considerably, thereby enhancing preventive and management strategies. The bibliometric analysis demonstrates the chronological trends of publications, highlighting the most influential studies related to skin photoaging.
Objective: This study aims to identify and analyze the top 100 most-cited articles related to skin photoaging to offer bibliometric information.
Front Med (Lausanne)
February 2025
Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Introduction: The General Data Protection Regulation ("GDPR") legal basis for obtaining consent for the processing of personal data for research purposes, where those purposes cannot be fully specified in advance, is provided for in Articles 6, 7 and Recital 33. However, GDPR's requirements for obtaining consent, as to the secondary use and sharing of data in research, have been argued to have generated confusion, whilst the conflicts between the Regulation itself, its practical application and research ethics are well-documented (1). The requirements for "informed consent", as defined within the GDPR, have not been well defined in the context of genome research or clinical trials (2), which has in turn led to the implementation and interpretation of the lawful basis to span into different idiosyncratic models.
View Article and Find Full Text PDFSyst Rev
March 2025
Department of Cardiology, Guang'Anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Background: Chinese classical prescriptions (CCPs) are commonly utilized in China as an adjuvant treatment for dilated cardiomyopathy (DCM). Nevertheless, there was insufficient systematic evidence data to show the advantages of CCPs plus current conventional therapy (CT) against DCM. This network meta-analysis (NMA) sought to evaluate and prioritize the six different CCP types' respective efficacies for DCM.
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