Interventional Cardiac Electrophysiology for the Management of Adults With Congenital Heart Disease.

Congenital heart disease (CHD) is the most common congenital anomaly in newborns. Advances in catheter and surgical techniques led to the majority of these patients surviving into adulthood, leading to evolving challenges due to the emergence of long-term complications such as arrhythmias. Interventional electrophysiology (EP) has had remarkable advances over the last few decades, and various techniques and devices have been explored to treat adult patients with CHD. This comprehensive review aims to summarize findings from recent studies exploring advances in the use of interventional electrophysiology to manage adult patients with CHD. While pacemaker therapy has some indications in adults with CHD, various long-term consequences include pacing-induced cardiomyopathy and complications requiring reintervention. Cardiac resynchronization therapy has shown promising results in some studies to treat CHD patients with heart failure, although further research to clarify guidelines is encouraged. Implantable cardiac defibrillators have demonstrated clear benefits in CHD patients and are indicated for primary prevention of sudden cardiac death, although selection criteria for secondary prevention of sudden cardiac death are uncertain. Catheter ablation has also been used for various atrial and ventricular arrhythmias in patients with CHD with high success rates, although the likelihood of success depends on patient characteristics and the type of arrhythmia, and multidisciplinary assessment is encouraged to improve the chance of successful therapy.