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| http://dx.doi.org/10.1016/j.xkme.2024.100939 | DOI Listing |
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Article Synopsis
- PTHrP and RBP4 are linked to worse kidney disease outcomes, and their relationship with PPARγ, a protective nuclear receptor, was investigated.
- The study examined levels of these proteins in different mouse models, including controls, diabetics, and those overexpressing PTHrP.
- Findings indicated that RBP4 and PTHrP levels increase during kidney pathology, suggesting that insulin and PPARγ play crucial roles in regulating their expression to maintain kidney health.
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