Hyalinizing trabecular tumor of the thyroid: A case report.

Oncol Lett

Department of Oncology, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong 261042, P.R. China.

Published: March 2025

A hyalinizing trabecular tumor (HTT), characterized by a trabecular growth pattern and notable hyalinization within the trabeculae, occurs at a rate of ~1%. As patients with HTT may be asymptomatic, accurate diagnosis is a challenge. Due to its resemblance to other tumors, such as papillary thyroid carcinoma and medullary thyroid carcinoma, a precise diagnosis necessitates both pathological and molecular examinations. Additionally, HTT is potentially malignant. The present study described the clinicopathological diagnosis of a patient with HTT; highlighting how an understanding of the clinical and pathological features of HTT is needed to provide an accurate differential diagnosis and thus tailor the treatment approach in order to effectively manage the disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726283PMC
http://dx.doi.org/10.3892/ol.2025.14865DOI Listing

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