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http://dx.doi.org/10.3760/cma.j.cn112148-20231219-00512 | DOI Listing |
J Antimicrob Chemother
January 2025
Pharmacy Department, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, Belgium.
Background: AUC-based dosing with validated Bayesian software is recommended as a good approach to guide bedside vancomycin dosing.
Objectives: To compare treatment and vancomycin-associated acute kidney injury (AKI) costs between Bayesian AUC-based dosing and conventional therapeutic drug monitoring (TDM) using steady-state plasma concentrations of vancomycin administered as continuous infusion in hospitalized non-critically ill patients with severe Gram-positive infection.
Methods: A cost-benefit analysis presented as a return on investment (ROI) analysis from a hospital perspective was conducted using a decision tree model (TDM versus AUC-based dosing) to simulate treatment cost (personnel, serum sampling and drug cost), vancomycin-associated AKI risk and cost up to 14 days.
Clin Optom (Auckl)
January 2025
Research Department, Southern College of Optometry, Memphis, TN, USA.
Purpose: To determine the performance of TOTAL30 for Astigmatism (T30fA; Alcon; Fort Worth, TX, USA) contact lenses (CLs) in existing CL wearers who are also frequent digital device users.
Methods: This 1-month, 3-visit study recruited adult, 18- to 40-year-old subjects who were required to use daily digital devices for at least 8 hours per day. All subjects were refit into T30fA CLs.
Bioelectrochemistry
January 2025
Graduate School of Engineering, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522 Japan.
Heparin concentration c in a blood extracorporeal circulation has been real-timely predicted based on the relaxation strength Δε at relaxation frequency f extracted by relaxation time distribution (RTD). The simulated extracorporeal circulation was conducted to optimize the number of Δε for the prediction of c using the porcine whole blood (WB) and low-leukocyte and -platelet blood (LLPB) under the condition of the gradual increment of c from 0 to 8 U/mL with constant flow rate and blood temperature. The experimental results show that among the three relaxation strengths Δε, Δε and Δε (in ascending order of frequency), Δε at f = 5.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Institute of Geotechnics, Slovak Academy of Sciences, Watsonova 45, 040 01 Košice, Slovakia.
In Slovakia, there are a number of contaminated sites that have occurred due to intensive mining, mineral processing, metallurgical activities, chemical industry, fossil fuel combustion, and industrial agriculture in the past. This paper summarizes the occurrence, chemistry, toxicity, and mineralogy of arsenic species related to soil and water contamination in Slovakia. Four main localities with arsenic exposure were identified.
View Article and Find Full Text PDFDiagnostics (Basel)
January 2025
Department of Thoracic Medicine, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Mechanical power (MP) refers to ventilator-delivered energy to the lungs, which may induce lung injury. We examined the relationship between MP and mortality in patients with acute respiratory distress syndrome (ARDS) who underwent prone positioning. This multicenter retrospective study included data on all patients admitted to the intensive care units of eight referral hospitals in Taiwan from October 2015 to March 2016, and in Chang Gung Memorial Hospital Linkou branch from January 2017 to October 2023.
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