Treatment modalities and trends for hospitalized patients with neovascular glaucoma: A retrospective study of 10 years.

To analyze the treatment modalities and trends for neovascular glaucoma (NVG) over the past 10 years, we conducted a retrospective analysis at Zhongshan Ophthalmic Center on 1331 NVG inpatients who received 1459 treatments for 1383 eyes between January 1, 2012, and December 31, 2021. Over time, we observed a progressive annual increase in both the number of patients and the volume of surgeries for NVG, with an annual percentage change (APC) of 10.23% (95% confidence interval [CI]: 5.5-15.2%, P = 0.001) and 11.59% (95% CI: 6.6-16.9%, P = 0.001), respectively. Drainage valve implantation (46.88%), cyclodestructive procedures (22.55%) and trabeculectomy (6.24%) were the three most commonly selected treatment options. The frequency of drainage valve implantation (APC = 6.59%, 95% CI = 0.9-12.6%, P = 0.028), cyclodestructive procedures (APC = 17.26%, 95% CI = 9.3-25.8%, P = 0.001) and trabeculectomy (APC = 21.93%, 95% CI = 1.6-46.3%, P = 0.036) increased. The proportion of drainage valve implantation gradually decreased (APC = -4.48%, 95% CI = -8.6 to -0.2%, P = 0.042), while that of cyclodestructive procedures increased (APC = 5.08%, 95% CI = 0.6-9.8%, P = 0.042), with no significant alteration observed in the proportion of trabeculectomy (APC = 9.26%, 95% CI = -8.8 to 30.9%, P = 0.290). Over the course of the study, both the cases of NVG and the volume of related surgeries escalated year by year. Among the three most frequently employed procedures-drainage valve implantation, cyclodestructive procedures and trabeculectomy-annual frequency trends revealed an increase in drainage valve implantation alongside a decreasing proportion, while cyclodestructive procedures exhibited a rising trend in both frequency and proportion; simultaneously, trabeculectomy showed an increasing frequency without a significant change in its proportion.