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Ternary Complex Components Responsible for Rapid LDL Internalization as Biomarkers for Breast Cancer Associated with Proliferation and Early Recurrence. | LitMetric
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Ternary Complex Components Responsible for Rapid LDL Internalization as Biomarkers for Breast Cancer Associated with Proliferation and Early Recurrence.

Elizabeth S McDonald Tien-Chi Pan Dhruv K Pant Melissa A Troester Andrew V Kossenkov David A Mankoff Robert H Mach Lewis A Chodosh

Cancer Res Commun

Department of Cancer Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

Published: February 2025

This first large-scale analysis of the putative ternary complex responsible for rapid low-density lipoprotein internalization in breast cancer reveals a link between component expression and recurrence, with prognostic implications for identifying patients needing supplemental posttreatment surveillance and/or additional therapeutic approaches.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11791746PMC
http://dx.doi.org/10.1158/2767-9764.CRC-23-0562DOI Listing

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