Although infection with is generally self-limited, it may cause refractory or life-threatening pneumonia with pulmonary or extrapulmonary complications. Necrotizing bronchitis is a rare condition with a high mortality rate. The present report describes a patient with mycoplasma pneumonia and necrotizing bronchitis that caused airway obstruction. A 7-year-old girl presented with fever and cough and was hospitalized. Her symptoms did not improve, and mild hypoxemia was observed. Fiberoptic bronchoscopy revealed diffuse bronchitis with necrotic and hemorrhagic material obstructing the bronchus. The necrotic tissue was removed directly, unblocking the airways. This case underscores the importance of fiberoptic bronchoscopy for early diagnosis and treatment of severe respiratory complications associated with Mycoplasma pneumoniae infection, such as necrotizing bronchitis. Early recognition and timely intervention are critical to improving patient outcomes in such cases.
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http://dx.doi.org/10.2147/IDR.S498411 | DOI Listing |
Cureus
December 2024
Laboratory of Infectious Diseases, Graduate School of Infection Control Sciences & Ōmura Satoshi Memorial Institute, Kitasato University, Tokyo, JPN.
Necrotizing soft tissue infections (NTSIs) represent a concept of necrotizing infections involving the skin, subcutaneous tissue, fascia, and muscle, and it is a potentially fatal disease. Early exploratory incision is strongly recommended for both the diagnosis and treatment of necrotizing soft tissue infections. Treatment of necrotizing soft tissue infections requires the administration of appropriate antimicrobial agents and adequate surgical debridement.
View Article and Find Full Text PDFVet Microbiol
January 2025
Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China. Electronic address:
The purpose of this study was to investigate whether RIPK3-mediated programmed cell death can promote the replication and transmission of renal infectious bronchitis virus in renal tubular epithelial cells. Primary renal tubular epithelial cells were extracted from 1 to 7 day old Hy-Line Brown chicks, cultured in vitro by type I collagenase digestion, and infected with 1MOI SX9 strain. Cell samples were collected at 12 hpi, 24 hpi, 36 hpi and 48 hpi for experimental exploration.
View Article and Find Full Text PDFInfect Drug Resist
January 2025
Department of Pediatrics, Zhejiang University School of Medicine Second Affiliated Hospital Jiashan Branch, the First People's Hospital of Jiashan, Jiashan, Zhejiang, 314100, People's Republic of China.
Although infection with is generally self-limited, it may cause refractory or life-threatening pneumonia with pulmonary or extrapulmonary complications. Necrotizing bronchitis is a rare condition with a high mortality rate. The present report describes a patient with mycoplasma pneumonia and necrotizing bronchitis that caused airway obstruction.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Alzheimer's disease (AD) poses a global health challenge, demanding innovative approaches for effective treatments. Clerodendrum infortunatum Linn. (Lamiaceae) is a shrub traditionally used as a medicinal plant to treat inflammation, skin diseases, and bronchitis.
View Article and Find Full Text PDFToxicol Appl Pharmacol
December 2024
Department of Pathology, Faculty of Veterinary Medicine, Cairo University, P.O. Box 12211, Giza, Egypt.
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