Background: Chronic apical periodontitis (AP) may influence the outcome of root canal treatment. Thus, it is important to diagnose AP using the best method available. This research was done to compare the diagnostic accuracy of parallel periapical radiography (PR) and different field of views (FOVs) of cone-beam computed tomography (CBCT).
Materials And Methods: This study was done on six human mandibles. After extraction of the teeth, periapical lesions with different sizes were prepared randomly by drilling a hole at the base of the socket using a bur. From among 67 sockets, 21 sockets had no lesion (control); then, all mandibles were scanned by CBCT with different FOVs and paralleling periapical technique radiography. The images were assessed by two examiners. The quantitative data were analyzed by intraclass correlation coefficient (ICC) and the qualitative data were analyzed by McNemar's test (α = 0.05). Sensitivity, specificity, and accuracy were calculated. Inter-observer agreement was assessed using kappa statistics for qualitative data and ICC for quantitative data.
Results: The quantitative scores were compared with the gold standard using ICC, which showed maximum agreement for the dental FOV of CBCT (93.3) and minimum agreement for PR (62.5) ( < 0.001). For qualitative data, maximum agreement was found for the dental FOV of CBCT (97.1%), and minimum agreement was reported for PR (59.7%). Kappa values were variable between 0.271 and 0.924 ( < 0.001). Maximum sensitivity was found for the dental FOV of CBCT (96%) and minimum sensitivity was observed for PR (51%). The inter-observer agreement was 0.922 for qualitative data and 0.90 for quantitative data ( < 0.001). There were no significant differences between CBCT with different FOVs and defect sizes (gold standard) while we found significant differences for periapical by defect sizes.
Conclusion: CBCT with dental FOV presents the highest sensitivity and diagnostic accuracy for detection and characterization of simulated AP.
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http://dx.doi.org/10.4103/drj.drj_466_23 | DOI Listing |
J Med Internet Res
January 2025
Knight Foundation of Computing & Information Sciences, Florida International University, Miami, FL, United States.
Background: Digital biomarkers are increasingly used in clinical decision support for various health conditions. Speech features as digital biomarkers can offer insights into underlying physiological processes due to the complexity of speech production. This process involves respiration, phonation, articulation, and resonance, all of which rely on specific motor systems for the preparation and execution of speech.
View Article and Find Full Text PDFJMIR AI
January 2025
Faculty of Social Science, Ruhr University Bochum, Bochum, Germany.
Background: Conversational agents (CAs) are finding increasing application in health and social care, not least due to their growing use in the home. Recent developments in artificial intelligence, machine learning, and natural language processing have enabled a variety of new uses for CAs. One type of CA that has received increasing attention recently is smart speakers.
View Article and Find Full Text PDFJMIR Res Protoc
January 2025
Institute of Medical Sociology and Rehabilitation Science, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Background: Acquired neurological diseases entail significant changes and influence the relationship between a patient and their significant other. In the context of long-term rehabilitation, those affected collaborate with health care professionals who are expected to have a positive impact on the lives of the affected individuals.
Objective: This study aims to examine the changes in the relationship between the patient and their loved ones due to acquired neurological disorders and the influence of health care professionals on this relationship.
JAMA Netw Open
January 2025
Department of Public Health and Preventive Medicine, State University New York (SUNY) Upstate Medical University, Syracuse, New York.
Importance: Environmental service workers (ESWs) have a critical role within the hospital infrastructure and are at the frontline of infection prevention. ESWs are highly trained in managing all forms of regulated waste, which includes biohazardous waste, and are responsible for the overall patient experience, janitorial work, and infection prevention. Without environmental services, patients have a 6 times greater risk of being infected by pathogens from patients who previously occupied their room.
View Article and Find Full Text PDFNeurology
January 2025
Department of Neurosurgery, Lenox Hill Hospital, Zucker School of Medicine at Hofstra/Northwell, New York, NY; and.
Background And Objectives: This systematic review aims to synthesize the current literature on the association between chemotherapy (CTX) and chemotherapy-related cognitive impairment (CRCI) with functional and structural brain alterations in patients with noncentral nervous system cancers.
Methods: A comprehensive search of the PubMed/MEDLINE, Web of Science, and Embase databases was conducted, and results were reported following preferred reporting items for systematic review and meta-analyses guidelines. Data on study design, comparison cohort characteristics, patient demographics, cancer type, CTX agents, neuroimaging methods, structural and functional connectivity (FC) changes, and cognitive/psychological assessments in adult patients were extracted and reported.
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