Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11724380 | PMC |
| http://dx.doi.org/10.20524/aog.2024.0937 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Daytime DNase-I Administration Protects Mice From Ischemic Stroke Without Inducing Bleeding or tPA-Induced Hemorrhagic Transformation, Even With Aspirin Pretreatment.
Stroke
February 2025
Neurovascular Research Unit, Pharmacology Department, Complutense Medical School, Instituto Investigación Hospital 12 Octubre, Madrid, Spain (G.D., B.D., A.M., J.M.P., I.L.).
Background: Acute ischemic stroke treatment typically involves tissue-type plasminogen activator (tPA) or tenecteplase, but about 50% of patients do not achieve successful reperfusion. The causes of tPA resistance, influenced by thrombus composition and timing, are not fully clear. Neutrophil extracellular traps (NETs), associated with poor outcomes and reperfusion resistance, contribute to thrombosis.
View Article and Find Full Text PDFSex steroid disrupting effects of nonsteroidal anti-inflammatory drugs on the Persian Gulf Arabian Sea bream, Acanthopagrus arabicus: In vitro model of environmental drug contamination.
Toxicol In Vitro
January 2025
Department of Basic Science, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran.
The presence of pharmaceuticals in aquatic ecosystems and their impact on humans and the environment are growing concerns in environmental health. This study aimed to evaluate the potential reproductive effects of diclofenac, ibuprofen, and aspirin on dissociated ovarian and testicular cells from Arabian Sea bream, Acanthopagrus arabicus. The cells were exposed to varying concentrations of the pharmaceuticals for 48 h.
View Article and Find Full Text PDFPurpose: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have risen exponentially in usage and have been shown to exert neuroprotective and anti-inflammatory effects across multiple organ systems. This study investigates whether GLP-1RAs influence the risk for age-related ocular diseases.
Design: Retrospective cohort study.
Platelet FcRγ inhibits tumor metastasis by preventing the colonization of circulating tumor cells.
Eur J Pharmacol
January 2025
State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, Jiangsu, 211198, PR China. Electronic address:
Fc receptor γ subunit (FcRγ) activation plays a crucial role in cancer carcinogenesis. Here, we aimed to uncover the impact of FcRγ on circulating tumor cells (CTC) colonization and the underlying mechanism. FcRγ deficient (FcRγ) mice were used to investigate the functional effects of FcRγ in cancer metastasis, and the results demonstrated that FcRγ deficiency significantly promotes metastasis.
View Article and Find Full Text PDFPrevalence of low-dose aspirin prophylaxis and its impact on maternal and fetal outcome in pre-eclamptic patients.
Int J Gynaecol Obstet
January 2025
Department of Obstetrics and Gynaecology, University of Benin Teaching Hospital (UBTH), Benin City, Nigeria.
Objective: To determine the prevalence of low-dose aspirin (LDA), missed opportunities in pre-eclampsia prevention and its impact on maternofetal outcomes among patients with pre-eclampsia.
Methods: A cross-sectional study of pre-eclampsia patients at the University of Benin Teaching Hospital, Benin City, Nigeria, prospectively recruited from February 1, 2023 to January 31, 2024. Data were collected using interviewer-administered questionnaires and medical records.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!