Introduction: In recent years, numerous hospitals have established in-house three-dimensional (3D) printing centers, enabling health-care facilities to leverage the transformative capabilities of additive manufacturing technology on their premises. With this emerging opportunity arises a necessity to undertake a thorough assessment of the manufactured tools employed in clinical practice. The objectives of this article are to describe the pathway of in-house printing and evaluate the accuracy of 3D-printed specific instruments.
Case Report: A case is reported along with the workflow for creating a patient model and cutting guide. The patient is a 76-year-old Caucasian woman with bone metastasis from a known renal cancer located in the pelvis. The model was used preoperatively, while the guide was used during surgery. Following this, the guide underwent computed tomography (CT) scanning, and a 3D digital model was reconstructed. Two dimensions, labeled A and B, were established. We compared pre-operative measurements, respectively, with measurements from the printed physical guide and from the rescanned post-operative digital model. Finally, A and B were measured on the bone defect on the patient's post-operative CT. Variation in axis A value between the mean of the first two groups was 0.5 mm and in axis B was 0.7 mm. On the printed physical guide, the mean of axis A was 73.5 mm, and the mean of axis B was 71.8 mm. Variation in A value between the mean of this group and the pre-operative was 1.7 mm and in B value was 0.5 mm.
Conclusion: The workflow used at our hospital was described with an example of how to evaluate the accuracy of in-house 3D printing. Results showed high accuracy of the printing method, a reliable correlation between desired and actual outcomes, and a short lead time.
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http://dx.doi.org/10.13107/jocr.2025.v15.i01.5142 | DOI Listing |
Extreme Mech Lett
March 2025
Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA.
Cutting soft materials on the microscale has emerging applications in single-cell studies, tissue microdissection for organoid culture, drug screens, and other analyses. However, the cutting process is complex and remains incompletely understood. Furthermore, precise control over blade geometries, such as the blade tip radius, has been difficult to achieve.
View Article and Find Full Text PDFKnee
January 2025
IULS-University Institute for Locomotion and Sports, Pasteur 2 Hospital, University Côte d'Azur, Nice, France; ICARE Team, Côte d'Azur University, Inserm, CNRS, Valrose Institute of Biology, Nice, France. Electronic address:
Background: Several studies have demonstrated the interest in patient-specific custom cutting guides in total knee arthroplasty (TKA), but clinical improvement remains debated. The purpose of this study was to evaluate the functional outcomes (Forgotten Joint Score, FJS) of patients undergoing individualized TKA compared with those receiving off-the-shelf (OTS) implants, both using patient-specific cutting guides with personalized alignment over a minimum follow up period of 12 months. We hypothesized that individualized TKA demonstrates significantly better functional outcomes than OTS TKA (FJS and percentage of patients reaching the minimum clinically important difference).
View Article and Find Full Text PDFZhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
January 2025
Department of Orthopedics, the First Affiliated Hospital of Ningbo University, Ningbo Zhejiang, 315000, P. R. China.
Objective: To investigate the feasibility and effectiveness of the novel bone hook combined with finger-guided technique in the treatment of irreducible intertrochanteric femoral fractures in elderly.
Methods: Between January 2021 and August 2023, 23 elderly patients with irreducible intertrochanteric femoral fractures were treated with the novel bone hook combined with finger-guided technique. There were 10 males and 13 females; the age ranged from 68 to 93 years (mean, 76.
Int J Radiat Oncol Biol Phys
January 2025
National Cancer Institute, Bethesda, MD. Electronic address:
This white paper examines the potential of pioneering technologies and artificial intelligence (AI)-driven solutions in advancing clinical trials involving radiotherapy. As the field of radiotherapy evolves, the integration of cutting-edge approaches such as radiopharmaceutical dosimetry, FLASH radiotherapy, image-guided radiation therapy (IGRT), and AI promises to improve treatment planning, patient care, and outcomes. Additionally, recent advancements in quantum science, linear energy transfer/relative biological effect (LET/RBE), and the combination of radiotherapy and immunotherapy create new avenues for innovation in clinical trials.
View Article and Find Full Text PDFCurr Opin Insect Sci
January 2025
Department of Experimental Biology, Genetics Area, University of Jaén, Paraje las Lagunillas s/n, 23071 Jaén, Spain; Department of General and Applied Biology, Institute of Biosciences/IB, UNESP - São Paulo State University, Rio Claro, São Paulo 13506-900, Brazil. Electronic address:
Insects, the most diverse group of animals, exhibit remarkable adaptability, playing both crucial and problematic roles in ecosystems. Recent advancements in genomic technologies, such as high-throughput sequencing, have provided unprecedented insights into the genetic foundations of insect adaptation. This review explores key methodologies, including de novo and reference-guided genome assemblies, and highlights cutting-edge technologies like second and third-generation sequencing, and hybrid techniques.
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