Background: To determine whether accounting for posterior corneal surgically induced astigmatism (SIA) would improve toric intraocular lens power calculation prediction error.
Methods: A total of 189 eyes of 148 patients undergoing routine cataract surgery were included in the study. Standard and posterior keratometry were measured pre- and postoperatively. Centroid SIA with standard keratometry and posterior keratometry were calculated separately. Prediction errors for postoperative refractive astigmatism at 4 weeks postoperatively were compared for Barrett Toric with predicted posterior corneal astigmatism (PPCA); Barrett Toric with preoperative measured posterior corneal astigmatism (MPCA); Barrett Toric with postoperative MPCA, which accounts for posterior corneal SIA.
Results: There was a significant increase in PCA magnitude postoperatively (p < 0.001), although a change of >0.3D occurred in only 3% of eyes. There was a postoperative rotation in the steep meridian of >10° in 32% of eyes. The Barrett Toric formula with PPCA yielded a significantly smaller refractive astigmatism prediction error compared to when a postoperative MPCA value was used (p < 0.01). Postoperative MPCA had a lower proportion of eyes within 0.50, 0.75 and 1.00D of predicted refractive astigmatism than PPCA or preoperative MPCA, although this was not statistically significant.
Conclusion: This study demonstrated postoperative changes in posterior corneal astigmatism magnitude and the orientation of the steep meridian. However, accounting for posterior keratometric SIA in the Barrett Toric formula does not improve refractive astigmatism prediction accuracy.
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http://dx.doi.org/10.2147/OPTH.S488571 | DOI Listing |
Cureus
December 2024
Cornea and Refractive Surgery, Al-Shifa Trust Eye Hospital, Rawalpindi, PAK.
Background: Glaucoma, particularly open-angle glaucoma (OAG), is a leading cause of irreversible blindness, associated with optic nerve damage, retinal ganglion cell death, and visual field defects. Corneal biomechanical properties and cellular components, such as corneal nerve and keratocyte densities assessed by in vivo confocal microscopy (IVCM), may serve as biomarkers for glaucoma progression. This study aimed to explore the relationship between corneal nerve parameters, keratocyte density, and optical coherence tomography (OCT)-derived retinal nerve fiber layer (RNFL) thickness in primary open-angle glaucoma (POAG) patients and controls.
View Article and Find Full Text PDFZhonghua Yi Xue Za Zhi
January 2025
Ophthalmology Center, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou310009, China.
To develop and validate a predictive model for assessing the risk of early postoperative high intraocular pressure (HIOP) following posterior chamber intraocular lens implantation. The clinical data of patients who underwent posterior chamber intraocular lens implantation at the Second Affiliated Hospital of Zhejiang University School of Medicine between May 2023 and April 2024 were retrospectively reviewed. Patients were divided into a modeling group and a validation group with a 7∶3 ratio using computerized random allocation.
View Article and Find Full Text PDFJ Clin Med
January 2025
Eye Clinic, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25121 Brescia, Italy.
This study aims to evaluate the repeatability of the Pentacam HR, comparing two different measurement modes (50-cornea fine and 25-3D scan) in patients affected by keratoconus. Multicenter retrospective study, conducted at Eye Clinic of the ASST-Spedali Civili-University of Brescia, Italy, and St. Paul's Eye Unit, Royal Liverpool University Hospital, United Kingdom.
View Article and Find Full Text PDFJ Clin Med
January 2025
Eye Unit, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, 25123 Brescia, Italy.
: The aim of this study was to evaluate the effect of a surgical technique for managing post-penetrating keratoplasty (PK) ectasia complicated by late endothelial failure (LEF). : A single-center pilot case series was conducted regarding consecutive patients affected by post-PK ectasia with late graft failure. Using a microkeratome, a single donor cornea was dissected to prepare a two-piece graft, comprising a larger anterior lamella made up of anterior stroma and a smaller posterior lamella made up of posterior stroma, Descemet's membrane, and endothelium.
View Article and Find Full Text PDFTransl Vis Sci Technol
January 2025
UCL Institute of Ophthalmology, University College London, London, UK.
Purpose: A human model able to simulate the manifestation of corneal endothelium decompensation could be advantageous for wound healing and future cell therapy assessment. The study aimed to establish an ex vivo human cornea endothelium wound model where endothelium function can be evaluated by measuring corneal thickness changes.
Methods: The human cornea was maintained in an artificial anterior chamber, with a continuous culture medium infusion system designed to sustain corneal endothelium and epithelium simultaneously.
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