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Whole-Heart Histological and CMR Validation of Electroanatomic Mapping by Multielectrode Catheters in an Ovine Model.
JACC Clin Electrophysiol
January 2025
Department of Cardiology, Westmead Hospital, Sydney, New South Wales, Australia; Westmead Applied Research Centre, University of Sydney, Sydney, New South Wales, Australia. Electronic address:
Background: Accurate electroanatomic mapping is critical for identifying scar and the long-term success of ventricular tachycardia ablation.
Objectives: This study sought to determine the accuracy of multielectrode mapping (MEM) catheters to identify scar on cardiac magnetic resonance (CMR) and histopathology.
Methods: In an ovine model of myocardial infarction, we examined the effect of electrode size, spacing, and mapping rhythm on scar identification compared to CMR and histopathology using 5 multielectrode mapping catheters.
Electrical graft assessment of machine-perfused hearts donated after circulatory death.
Ann Cardiothorac Surg
November 2024
Translational Electrophysiology Lab, Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands.
Article Synopsis
- Normothermic ex situ heart perfusion (ESHP) improves the availability of hearts from donors after circulatory death (DCD), but current methods for assessing heart function, like monitoring lactate levels, are not very effective.* -
- This study evaluated the use of high-resolution cardiac mapping during ESHP to analyze the electrical function of DCD hearts, revealing that lower voltages could indicate myocardial injury.* -
- The results from mapping ten DCD hearts showed that the technique is safe and feasible, and it could provide valuable insights into graft function for marginal donor hearts.*
Outcome of repeat ablation for premature ventricular contractions in patients with prior ablation failure: Impact of advanced techniques.
Heart Rhythm
November 2024
Cardiovascular Division, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:
Background: The utility of repeat ablation for premature ventricular contractions (PVCs) after prior ablation failure is not clear.
Objective: The purpose of this study was to assess the outcomes of repeat ablation and the use of different techniques in patients who failed prior PVC ablation.
Methods: We reviewed 239 consecutive patients who underwent PVC ablation.
Lesion characteristics of long application time ablation using unipolar half-normal saline irrigation and bipolar normal saline irrigation.
Indian Pacing Electrophysiol J
November 2024
Cardiovascular Research of Graduate School of Health Sciences, Niigata University School of Medicine, Niigata, Japan. Electronic address:
Introduction: Unipolar radiofrequency (RF) ablation using half-normal saline irrigation (UNIP-HNS) and bipolar RF ablation using normal saline irrigation (BIP-NS) are effective to treat arrhythmias from inside thick myocardium. However, differences between these two ablations when using a long application time had not fully been studied.
Methods: UNIP-HNS, BIP-NS and unipolar RF ablation using normal saline irrigation (UNIP-NS) were applied for 120 s (30 W and 20-g contact) to porcine endocardial wall (≧15.
Case Report: Epi-endocardial bridges in refractory cavotricuspid isthmus-dependent atrial flutter: technical analysis of epi-endocardial breakthrough.
Front Cardiovasc Med
August 2024
Clinical and Rehabilitation Cardiology Division, San Filippo Neri Hospital, Rome, Italy.
Background: Typical isthmus-dependent atrial flutter (AFL) is traditionally treated through radiofrequency (RF) ablation to create a bidirectional conduction block across the cavo-tricuspid isthmus (CTI) in the right atrium. While this approach is successful in many cases, certain anatomical variations can present challenges, making CTI ablation difficult.
Methods: We enrolled four patients with typical counter-clockwise AFL who displayed an epicardial bridge at the CTI.
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