Introduction: End-user evaluation of the impact of evidence syntheses is critical to demonstrating value. This study presents results of a survey evaluating the impact of rapid reviews undertaken by two teams based in Melbourne, Australia and Hamilton, Canada.
Methods: Clients were invited to participate in a short, written survey following delivery of a rapid review. Survey items encompassed reach, usefulness and format; interactions with the review teams; and overall satisfaction.
Results: Twenty-five completed surveys from 53 invitations were received pertaining to 19 rapid reviews conducted between September 2021 and October 2023. Topics encompassed COVID-19, health and behaviour change; reports were an average of 31 pages; and were delivered over an average of 62 days. Evaluation findings were positive, with high satisfaction with reports and service delivery; very high satisfaction with report structure and length; good evidence of reach (reports read by decision makers and cited in other documents); and evidence that the rapid reviews made contributions to strategic planning, policy and program funding decisions.
Conclusion: Rapid reviews are making impactful contributions, alongside other inputs, to policy and practice. Further research is required to build this evaluation dataset; examine the balance between timeliness and methodological rigor in evidence synthesis; and explore models of delivery and capacity within and outside of government. It is also critical to promote implementation efforts to harness the full potential of rapid reviews and other evidence syntheses to impact the lives of citizens.
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http://dx.doi.org/10.1016/j.jclinepi.2025.111673 | DOI Listing |
ACS Biomater Sci Eng
January 2025
J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611, United States.
The complexation of nucleic acids and collagen forms a platform biomaterial greater than the sum of its parts. This union of biomacromolecules merges the extracellular matrix functionality of collagen with the designable bioactivity of nucleic acids, enabling advances in regenerative medicine, tissue engineering, gene delivery, and targeted therapy. This review traces the historical foundations and critical applications of DNA-collagen complexes and highlights their capabilities, demonstrating them as biocompatible, bioactive, and tunable platform materials.
View Article and Find Full Text PDFExpert Rev Mol Diagn
January 2025
Hebei Provincial Center for Clinical Laboratories, Shijiazhuang, China, the Second Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, People's Republic of China.
Introduction: Rapid and accurate laboratory diagnosis is essential for the effective treatment of bloodstream infection (BSI).
Areas Covered: This review aims to address novel and traditional approaches that exhibit different performance characteristics in the diagnosis of BSI. In particular, the authors will discuss the pros and cons of the blood culture-based phenotypic methods, nucleic acid-targeted molecular methods, and host response-targeted biomarker detection in the diagnosis of BSI.
Dalton Trans
January 2025
National Engineering Research Center for Domestic & Building Ceramics, School of Materials Science and Engineering, Jingdezhen Ceramic University, Jingdezhen 333403, China.
Due to a lack of spatially resolved characterization studies on statistical and individual particle microstructure at multiple scales, a knowledge gap exists in understanding the mechanistic link between rapid performance failure and atomic-scale structure degradation in single-crystalline Ni-rich battery cathodes. In a recent publication in , Huang developed a multi-crystal rocking curve technique (combining X-ray and electron microscopy to capture both statistical and individual lattice distortions), which enables multiscale observations and further proves that the accumulation of the unrecoverable lattice rotation in cathodes upon repeated cycling exacerbates mechanical failure and electrochemical decay. The elucidation of failure mechanisms in single-crystalline cathodes offers valuable insights into the development of long-lasting and high-energy-density cathodes in next-generation batteries, encompassing strategies to mitigate lattice rotation and enhance lattice structure tolerance against lattice distortion within individual particles.
View Article and Find Full Text PDFCrit Rev Microbiol
January 2025
Oral Microbiology, Bristol Dental School, University of Bristol, United Kingdom.
This review discusses the chemical properties, synthesis and detection, and biological functions of a molecular group of cis-2-unsaturated fatty acids, containing fatty acid carbon chains of various lengths and cis double-bond configurations, known as the diffusible signaling factor family (DSFF). Early postulation of the conserved nature of the DSFF among Gram-negative bacteria have now been challenged by the latest evidences that unraveled their presence in a various other distinct microorganisms. Over the last decade, a significant depth and breadth of understanding has been made on the multifaceted functions of DSFFs among bacteria, and their interactions with evolutionarily divergent fungi, plants insects and small animals.
View Article and Find Full Text PDFJ Food Sci Technol
February 2025
Department of Chemical Engineering, Indian Institute of Technology, New Delhi, 110062 India.
Unlabelled: The use of pesticides in agricultural produce is continuously increasing and it raises the question of whether the food is safe or not. Only 0.1% of the sprayed pesticide reaches its target and the rest acts as a contaminant in soil and the environment, thus contaminating the future foods as well.
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