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http://dx.doi.org/10.1002/hep.1840050237 | DOI Listing |
Biochem Med Metab Biol
August 1990
Department of Biochemistry (Faculty of Pharmacy), University of Santiago de Compostela, Spain.
We report the free, acyl-, and total carnitine contents of 49 clinically healthy volunteers and 167 chronic alcoholics with various clinically and/or anatomopathologically identified degrees of hepatic affection. There was a gradual upward trend in carnitine levels as the degree of hepatic affection increased. In cirrhotic patients, both free and acylcarnitine levels were significantly higher than normal, but there was no systematic hypercarnitinemia in other stages of alcoholism; on the contrary, noncirrhotic alcoholic patients accounted for 82.
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