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On the pursuit of reproducibility: the importance of large sample sizes in psychoimmunology.
Transl Psychiatry
January 2025
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Peripheral inflammatory markers (PIMs), such as C-reactive protein (CRP) or white blood cell count (WBC), have been associated with depression severity in meta-analyses and large cohort studies. However, in typically-sized psychoimmunology studies (N < 200) that explore associations between PIMs and neurobiological/psychosocial constructs related to depression and studies that examine less-studied PIMs (e.g.
View Article and Find Full Text PDFBiomarkers and Social Determinants in atherosclerotic Arterial Diseases: A Scoping Review.
Ann Vasc Surg
January 2025
Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy; Interuniversity Center of Phlebolymphology (CIFL), "Magna Graecia" University, 88100 Catanzaro, Italy. Electronic address:
Background: Arterial diseases like coronary artery disease, carotid stenosis, peripheral artery disease, and abdominal aortic aneurysm have high morbidity and mortality, making them key research areas. Their multifactorial nature complicates patient treatment and prevention. Biomarkers offer insights into the biochemical and molecular processes, while social factors also significantly impact patients' health and quality of life.
View Article and Find Full Text PDFDoes women empowerment impact child well-being? Evidence from India.
Soc Sci Med
January 2025
Department of Humanities and Social Sciences, National Institute of Technology Silchar, Silchar, 788010, Assam, India. Electronic address:
This study intends to examine how women's empowerment directly or indirectly impacts their children's well-being. Since prior research primarily focussed on the effects of maternal empowerment on specific domains of child well-being, such as healthcare or education, this study seeks to explore a more comprehensive understanding of child well-being, where child well-being is quantified using four domains, viz., physical well-being, psycho-social well-being, educational well-being and awareness of safety.
View Article and Find Full Text PDFThe contribution of cognitive disengagement syndrome symptoms to depressive symptoms among pediatric brain tumor survivors.
J Pediatr Psychol
January 2025
The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.
Objective: Pediatric brain tumor survivors (PBTS) are at risk for neurocognitive late effects that can resemble symptoms of cognitive disengagement syndrome (CDS). In the current study, we compared the CDS symptoms of PBTS to those of healthy comparison classmates (CC) and examined whether CDS might explain group differences in depressive symptoms. We also explored whether CDS symptoms were associated with engagement-based coping strategies and stress responses, thereby testing one mechanism by which CDS could lead to affective difficulties.
View Article and Find Full Text PDFInterest in digital health tools for miscarriage support: A qualitative assessment of Canadian women facing early pregnancy loss.
Womens Health (Lond)
January 2025
Vitala Global Foundation, Vancouver, BC, Canada.
Background: Early pregnancy loss (EPL) occurs in 10%-15% of all pregnancies but remains an underrecognized and undertreated condition. In Canada, resources to support individuals and their partners facing EPL remain scarce despite a high burden of psychosocial sequelae. Digital health tools hold the potential to fill important gaps in reproductive healthcare.
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