Nonsmooth nonconvex optimization problems are pivotal in engineering practice due to the inherent nonsmooth and nonconvex characteristics of many real-world complex systems and models. The nonsmoothness and nonconvexity of the objective and constraint functions bring great challenges to the design and convergence analysis of the optimization algorithms. This paper presents a smooth gradient approximation neural network for such optimization problems, in which a smooth approximation technique with time-varying control parameter is introduced for handling nonsmooth nonregular objective functions. In addition, a hard comparator function is introduced to ensure that the state solution of the proposed neural network remains within the nonconvex inequality constraint sets. Any accumulation point of the state solution of the proposed neural network is proved to be a stationary point of the nonconvex optimization under consideration. Furthermore, the neural network demonstrates the ability to find optimal solutions for some generalized convex optimization problems. Compared with the related neural networks, the constructed neural network has weaker convergence conditions and simpler algorithm structure. Simulation results and an application in optimizing condition number verify the practical applicability of the presented algorithm.
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http://dx.doi.org/10.1016/j.neunet.2024.107121 | DOI Listing |
BMC Health Serv Res
January 2025
Department of Industrial Engineering, Dalhousie University, PO Box 15000, Halifax, B3H 4R2, NS, Canada.
Background: The growing demand for healthcare services challenges patient flow management in health systems. Alternative Level of Care (ALC) patients who no longer need acute care yet face discharge barriers contribute to prolonged stays and hospital overcrowding. Predicting these patients at admission allows for better resource planning, reducing bottlenecks, and improving flow.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Human Anatomy, Graduate School, Inner Mongolia Medical University, Hohhot, 010010, Inner Mongolia, China.
Purpose: The study aimed to develop a deep learning model for rapid, automated measurement of full-spine X-rays in adolescents with Adolescent Idiopathic Scoliosis (AIS). A significant challenge in this field is the time-consuming nature of manual measurements and the inter-individual variability in these measurements. To address these challenges, we utilized RTMpose deep learning technology to automate the process.
View Article and Find Full Text PDFBMC Bioinformatics
January 2025
College of Artificial Intelligence, Nanjing Agricultural University, Weigang No.1, Nanjing, 210095, Jiangsu, China.
Antimicrobial peptides (AMPs) have been widely recognized as a promising solution to combat antimicrobial resistance of microorganisms due to the increasing abuse of antibiotics in medicine and agriculture around the globe. In this study, we propose UniAMP, a systematic prediction framework for discovering AMPs. We observe that feature vectors used in various existing studies constructed from peptide information, such as sequence, composition, and structure, can be augmented and even replaced by information inferred by deep learning models.
View Article and Find Full Text PDFCommun Biol
January 2025
Institute for Automation and Applied Informatics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany.
Biomedical research increasingly relies on three-dimensional (3D) cell culture models and artificial-intelligence-based analysis can potentially facilitate a detailed and accurate feature extraction on a single-cell level. However, this requires for a precise segmentation of 3D cell datasets, which in turn demands high-quality ground truth for training. Manual annotation, the gold standard for ground truth data, is too time-consuming and thus not feasible for the generation of large 3D training datasets.
View Article and Find Full Text PDFNPJ Digit Med
January 2025
School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
The current approach to fetal anomaly screening is based on biometric measurements derived from individually selected ultrasound images. In this paper, we introduce a paradigm shift that attains human-level performance in biometric measurement by aggregating automatically extracted biometrics from every frame across an entire scan, with no need for operator intervention. We use a neural network to classify each frame of an ultrasound video recording.
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