AI Article Synopsis

  • The study focuses on the outcomes of aortic valve replacement (AVR) in young Moroccan patients with severe aortic regurgitation and impaired left ventricle function.
  • A total of 42 out of 110 patients with significant aortic regurgitation and an ejection fraction of ≤35% underwent AVR, showing a low immediate postoperative mortality rate of 4.7%.
  • Long-term follow-up indicated a high survival rate of 86.8% after 15 years, along with significant clinical improvements and increased left ventricle ejection fraction post-surgery.

Article Abstract

Background: Surgical management of patients with severe aortic regurgitation (AR) in the setting of significantly impaired left ventricle (LV) function generally carries very high operative risk. The aim of this study is to assess the short and long-term outcomes of aortic valve replacement (AVR) in a selected young Moroccan population.

Materiel And Methods: This is a retrospective study between January 2008 and June 2022 including all patients who underwent AVR for massive isolated AR with an LV ejection fraction EF ≤35%.

Results: In this center, a total of 3820 patients were operated for valvular disease, from which 110 had important AR. Overall, 42 patients of 110 patients had an LV ejection fraction≤35%, and benefited from AVR. Rheumatic cause was predominant (50%). Preoperative characteristics find an average age of 46.3 ±14.4 years with male prevalence. Only two deaths are noted in the immediate postoperative period. At the 15 years follow-up, the survival was 86.8%. Clinical improvement was present in the majority of patients. The mean LVEF post-AVR has increased by an average of 16% with proof of reverse remodeling.

Conclusions: In this series, patients benefited largely from AVR with good postoperative outcomes. The global operative mortality was acceptable (4.7%). The long-term survival (86.8%) was better than that described in the western series. Therefore, our results should encourage a surgical approach for those patients.

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Source
http://dx.doi.org/10.1016/j.ancard.2024.101859DOI Listing

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