Determining whether preoperative performance-based knee function predicts postoperative performance-based knee function and whether patient-reported outcome measures (PROMs) completed by participants can detect these changes could significantly enhance the planning of postoperative rehabilitation for patients following total knee arthroplasty (TKA). This study aims to collect data on performance-based knee function using inertial measurement units (IMUs) worn by participants both preoperatively and postoperatively. PROMs will be completed by the patients before and after surgery to assess their ability to detect the same changes in performance-based knee function measured by the sensors. Additionally, the study will investigate the correlation between the degree of knee alignment correction and postoperative performance-based knee function in participants after TKA.
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http://dx.doi.org/10.3390/s25010118 | DOI Listing |
Pharmaceutics
January 2025
Department of Pharmacology, School of Medicine, University of Mostar, 88000 Mostar, Bosnia and Herzegovina.
Background: This is a novel rat study using native peptide therapy, focused on reversing quadriceps muscle-to-bone detachment to reattachment and stable gastric pentadecapeptide BPC 157 per-oral therapy for shared muscle healing and function restoration.
Methods: Pharmacotherapy recovering various muscle, tendon, ligament, and bone lesions, and severed junctions (i.e.
Nutrients
January 2025
Department of Anesthesiology, Cathay General Hospital, Taipei 280, Taiwan.
Knee osteoarthritis (OA) is a common and debilitating disorder marked by joint degradation, inflammation, and persistent pain. This study examined the possible therapeutic effects of curcumin and vitamin D on OA progression and pain in a rat knee OA model by anterior cruciate ligament transection and meniscectomy (ACLT + MMx). Male Wistar rats were categorized into five groups: control, curcumin-treated (100 mg/kg/day), vitamin D-treated (25 µg/kg/day), a combination of vitamin D and curcumin, and sham-operated.
View Article and Find Full Text PDFNutrients
January 2025
Grupo de Investigación en Calidad de Vida y Salud, Departamento de Ciencias de la Salud, Universidad Europea de Valencia, 03016 Alicante, Spain.
Introduction: Osteoarthritis (OA) is the most prevalent form of arthritis and affects over 528 million people worldwide. Degenerative joint disease involves cartilage degradation, subchondral bone remodeling, and synovial inflammation, leading to chronic pain, stiffness, and impaired joint function. Initially regarded as a "wear and tear" condition associated with aging and mechanical stress, OA is now recognized as a multifaceted disease influenced by systemic factors such as metabolic syndrome, obesity, and chronic low-grade inflammation.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Faculty of Sports Science, Ningbo University, Ningbo 315211, China.
Barbell squats are commonly used in strength training, but the anterior-posterior displacement of the Center of Mass (COM) may impair joint stability and increase injury risk. This study investigates the key factors influencing COM displacement during different squat modes.; Methods: This study recruited 15 male strength training enthusiasts, who performed 60% of their one-repetition maximum (1RM) in the Front Barbell Squat (FBS), High Bar Back Squat (HBBS), and Low Bar Back Squat (LBBS).
View Article and Find Full Text PDFSensors (Basel)
January 2025
Department of Automation, Tsinghua University, Beijing 100084, China.
Squatting is a fundamental and crucial movement, often employed as a basic test during robot commissioning, and it plays a significant role in some service industries and in cases when robots perform high-dynamic movements like jumping. Therefore, achieving continuous and precise squatting actions is of great importance for the future development of humanoid robots. In this paper, we apply three-particle model predictive control (TP-MPC) combined with weight-based whole-body control (WBC) to a humanoid robot.
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