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Reduced-dose CT scan of colorectal cancer.
Abdom Radiol (NY)
January 2025
Department of Radiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Safety and toxicity of Iopofosine I 131 (CLR 131) with external beam radiation therapy in recurrent or metastatic head and neck cancer: results of a phase 1 single-centre, open-label, single-arm, dose escalation and dose expansion study.
EBioMedicine
December 2024
Department of Human Oncology, UW School of Medicine and Public Health, Madison, WI, USA.
Background: Re-irradiation of recurrent head and neck cancer (HNC) is often limited by tumour adherence to critical structures and/or radiation tolerance of critical normal tissues. Iopofosine I 131 (CLR 131) is a targeted small molecular phospholipid ether (PLE) drug conjugate that delivers iodine-131 selectively to tumour cells. We conducted a phase 1, single-centre, open-label study to determine whether CLR 131 given with reduced dose of external beam radiation therapy (EBRT) would be tolerable and feasible.
View Article and Find Full Text PDFPreoperative planning for shoulder arthroplasty is feasible with computed tomography at lower-than-conventional radiation doses.
J Shoulder Elbow Surg
October 2024
Department of Orthopedic Surgery, Duke University School of Medicine, Durham, NC, USA.
Article Synopsis
- The study investigates the effectiveness of reducing radiation doses in CT scans used for planning shoulder arthroplasty, aiming to minimize patient exposure to ionizing radiation.
- Ten CT scans were conducted utilizing different radiation dose levels (100%, 70%, and 30%) to measure shoulder parameters manually and via software, with strict tolerance levels set for preoperative planning.
- Results indicated that both automated and manual measurements taken from the 70% and 30% dose images were generally accurate enough to be considered viable for preoperative planning, with high agreement in key shoulder measurements across the varying dose levels.
Ultralow dose coronary calcium scoring CT at reduced tube voltage and current by using deep learning image reconstruction.
Eur J Radiol
December 2024
Department of Radiology, Affiliated Hospital of Hebei University, Baoding 071000, China. Electronic address:
Objective: To explore the potential of the deep learning reconstruction (DLR) for ultralow dose calcium scoring CT (CSCT) with simultaneously reduced tube voltage and current.
Methods: In this prospective study, seventy-five patients (group A) undergoing routine dose CSCT (120kVp/30mAs) were followed by a low dose (120kVp/20mAs) scan and another 81 (group B) were followed by an ultralow dose (80kVp/20mAs) scan. The hybrid iterative reconstruction was used for the routine dose data while the DLR for data of reduced dose.
Image Quality Evaluation for Brain Soft Tissue in Neuroendovascular Treatment by Dose-Reduction Mode of Dual-Axis "Butterfly" Scan.
AJNR Am J Neuroradiol
January 2025
From the Department of Stroke and Cerebrovascular Diseases (H.H., Y.I., K,H., A.M., H.Y., Y.M.), University of Tsukuba Hospital, Ibaraki, Japan.
Background And Purpose: Flat panel conebeam CT (CBCT) is essential for detecting hemorrhagic complications during neuroendovascular treatments. Despite its superior image quality and trajectory over conventional CBCT (circular scan), the dual-axis butterfly scan has a slightly higher radiation dose relative to conventional CBCT. This study evaluates the image quality in dose-reduction mode to uncover the appropriate radiation dose for the butterfly scan.
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