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Aptamer-molecularly imprinted polymer sensors for the detection of bacteria in water.
Biosens Bioelectron
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Department of Electronic and Electrical Engineering, University of Bath, Bath, BA2 7AY, United Kingdom; Centre for Bioengineering & Biomedical Technologies (CBio), University of Bath, Bath, BA2 7AY, United Kingdom. Electronic address:
Bacteria pose a significant threat to human health as they can cause diseases and outbreaks; therefore rapid, easy, and specific detection of bacteria in a short time is crucial. Various methods such as polymerase chain reaction and enzyme-linked immunosorbent assay have been developed for bacteria detection. However, most of these methods require sample preparation, trained personnel, and 2-4 days for identification.
View Article and Find Full Text PDFPOINT: Should Multiplex Molecular Panels Be Performed on All Patients With Community Acquired Pneumonia? Yes.
Chest
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Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL. Electronic address:
Time-resolved single-cell secretion analysis microfluidics.
Lab Chip
January 2025
Department of Biomedical Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong, Hong Kong, China.
Revealing how individual cells alter their secretions over time is crucial for understanding their responses to environmental changes. Key questions include: When do cells modify their functions and states? What transitions occur? Insights into the kinetic secretion trajectories of various cell types are essential for unraveling complex biological systems. This review highlights seven microfluidic technologies for time-resolved single-cell secretion analysis: 1.
View Article and Find Full Text PDFPortable paper-based microfluidic devices with CuAgS NPs modification for multiplex intelligent visualized detection of adrenaline and glucose simultaneously.
Anal Chim Acta
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Center for Quantum Sciences and School of Physics, Northeast Normal University, Changchun, 130117, China.
Background: Adrenaline and glucose are essential biomarkers in human body for maintaining metabolic balance. Abnormal levels of adrenaline and glucose are associated with various diseases. Therefore, it is important to design portable, on-site devices for rapid adrenaline and glucose analysis to safeguard health.
View Article and Find Full Text PDFBehind the scenes of cellular organization: Quantifying spatial phenotypes of puncta structures with statistical models including random fields.
Mol Biol Cell
January 2025
Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, the Netherlands.
The cellular interior is a spatially complex environment shaped by non-trivial stochastic and biophysical processes. Within this complexity, spatial organizational principles-also called spatial phenotypes-often emerge with functional implications. However, identifying and quantifying these phenotypes in the stochastic intracellular environment is challenging.
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