Membranes have been used as versatile tools for the separation of various natural products; however, the selective separation of structural analogs of natural products using membranes remains challenging. In this study, biocomposite membranes based on poly(ionic liquids) and different natural fibers (jute, cotton, or wool) were successfully prepared. Natural fibers can regulate the microstructure and improve the mechanical properties of membranes. Fourier transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, scanning electron microscopy, X-ray photoelectron spectroscopy, atomic force microscopy, Brunauer-Emmett-Teller analysis, and thermo gravimetric analysis were used to characterize the membranes. The membranes were used to separate tanshinone homologs (tanshinone I, tanshinone IIA, cryptotanshinone, and dihydrotanshinone I), allowing cryptotanshinone to penetrate the membrane while rejecting tanshinone I. A maximal selectivity of 44.57 % was obtained for the tanshinone homologs using a one-step separation protocol. These poly(ionic liquids)/natural fiber membranes possess high water flux, good self-cleaning, and good antibacterial properties. The membranes were effective in separating tanshinone homologs and have the potential to separate other natural homologs.
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http://dx.doi.org/10.1016/j.ijbiomac.2025.139568 | DOI Listing |
Int J Biol Macromol
January 2025
Institute of Bast Fiber Crops & Center of Southern Economic Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, China. Electronic address:
Membranes have been used as versatile tools for the separation of various natural products; however, the selective separation of structural analogs of natural products using membranes remains challenging. In this study, biocomposite membranes based on poly(ionic liquids) and different natural fibers (jute, cotton, or wool) were successfully prepared. Natural fibers can regulate the microstructure and improve the mechanical properties of membranes.
View Article and Find Full Text PDFMetabolites
August 2024
Key Laboratory of Plant Secondary Metabolism and Regulation in Zhejiang Province, College of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou 310018, China.
is one of the famous traditional Chinese medicines for treating cardiovascular and cerebrovascular diseases. Tanshinone and phenolic acids are the main active compounds of , whereas the distribution patterns of the two kinds of components are still unclear among spp. In this work, high-performance liquid chromatography was applied to analyze the distribution patterns of major components in the roots and leaves of 58 spp.
View Article and Find Full Text PDFJ Ethnopharmacol
December 2024
Key Laboratory of TCM-information Engineer of State Administration of TCM, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beisanhuan East Road No. 11, Chaoyang District, Beijing, 100029, China. Electronic address:
Ethnopharmacological Relevance: Salvia miltiorrhiza Bge. (SMB) is an herbal medicine extensively used for improving metabolic disorders, including Nonalcoholic fatty liver disease (NAFLD). However, the potential material basis and working mechanism still remained to be elucidated.
View Article and Find Full Text PDFJ Nanobiotechnology
April 2024
Jiangsu Clinical Innovation Center of Digestive Cancer of Traditional Chinese Medicine, Nanjing, Jiangsu, 210028, China.
The insufficient abundance and weak activity of tumour-infiltrating lymphocytes (TILs) are two important reasons for the poor efficacy of PD-1 inhibitors in hepatocellular carcinoma (HCC) treatment. The combined administration of tanshinone II (TSA) and astragaloside IV (As) can up-regulate the abundance and activity of TILs by normalising tumour blood vessels and reducing the levels of immunosuppressive factors respectively. For enhancing the efficacy of PD-1 antibody, a magnetic metal-organic framework (MOF) with a homologous tumour cell membrane (Hm) coating (Hm@TSA/As-MOF) is established to co-deliver TSA&As into the HCC microenvironment.
View Article and Find Full Text PDFJ Integr Neurosci
March 2024
Department of Pharmacy, Lanzhou University Second Hospital, 730030 Lanzhou, Gansu, China.
Background: Tanshinone IIA (TSIIA) is an element of the effective ingredients of Bunge (Labiatae), exhibits a significant therapeutic effect in brain neuroprotection. The focus of this study was the examination of synaptic plasticity of in Mg2+-free-induced epileptic hippocampus neurons and how TSIIA protects against it.
Methods: The purity of the primary hippocampal neurons extracted from Sprague Dawley rats was assessed within 24 hours by microtubule-associated protein (MAP2) immunofluorescence staining.
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