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The efficacy of curcumin-piperine supplementation in patients with nonproliferative diabetic retinopathy: An optical coherence tomography angiography-based randomized controlled trial.
J Res Med Sci
October 2024
Department of Community Nutrition, Food Security Research Center, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Diabetic retinopathy (DR) is one of the complications of diabetes. This study was conducted to investigate the effect of curcumin-piperine on laboratory factors and macular vascular in DR.
Materials And Methods: The present study was a randomized, placebo-controlled, double-blind, parallel-arm clinical trial that was conducted on 60 patients with DR aged 30-65 years.
The effect of curcumin-piperine supplementation on lipid profile, glycemic index, inflammation, and blood pressure in patients with type 2 diabetes mellitus and hypertriglyceridemia.
Phytother Res
November 2024
Nutrition and Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Article Synopsis
- Type 2 diabetes mellitus (T2DM) is a condition characterized by insulin resistance and related health issues, and this study looked at the potential benefits of a curcumin-piperine combination on patients with T2DM and high triglycerides.
- In a 12-week double-blind trial involving 72 participants, those receiving curcumin-piperine showed significant reductions in triglycerides and fasting blood glucose levels compared to a placebo group.
- While overall mood and energy levels improved in the curcumin-piperine group, other health indicators like blood pressure and cholesterol levels did not show significant differences between the groups.
The Mechanism of Anti-Viral Activity of a Novel, Hydroponically Selenium-Enriched Garlic Powder (SelenoForce) Against SARS-CoV-2 Virus.
Glob Adv Integr Med Health
August 2024
Sami-Sabinsa Group Limited, Bangalore, India.
Abstract: The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is far from over as new strains are emerging all over the world. Selenium as a micronutrient is important for immunity and also has anti-viral activity.
Objective: The study evaluated the activity of a Selenium enriched garlic powder (SeGP or SelenoForce) against SARS-CoV-2 viral replication in vitro and explored its possible mechanism of action.
The Neuroprotective Effects of Extract in SHSY-5Y Neuronal Cells by Upregulating BDNF Gene Expression under LPS Induced Inflammation.
Nutrients
June 2024
Department of Horticultural Sciences, Texas A&M University, College Station, TX 77843, USA.
The brain-derived neurotrophic factor (BDNF) plays a crucial role during neuronal development as well as during differentiation and synaptogenesis. They are important proteins present in the brain that support neuronal health and protect the neurons from detrimental signals. The results from the present study suggest BDNF expression can be increase up to ~8-fold by treating the neuroblastoma cells SHSY-5Y with an herbal extract of (50 μg/mL) and ~5.
View Article and Find Full Text PDFEvaluation of the effectiveness of curcumin and piperine co-supplementation on inflammatory factors, cardiac biomarkers, atrial fibrillation, and clinical outcomes after coronary artery bypass graft surgery.
Clin Nutr ESPEN
August 2024
Nutrition and Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran; Anesthesia and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address:
Background: Coronary artery bypass graft (CABG) is one of the preferred treatments for patients with heart problems, especially in individuals with other comorbidities and when multiple arteries are narrowed. This study aimed to assess the effects of administrating curcumin-piperine on patients who underwent CABG surgery.
Methods: This was a randomized, double-blind, placebo-controlled clinical trial, in which 80 eligible adults who underwent CABG surgery, were randomized into 4 groups.
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