Dura fenestration is non-inferior and with lower complication incidence compared to augmented duraplasty in decompressive craniectomy.

Decompressive craniectomy is a procedure for managing elevated intracranial pressure (ICP). However, it carries a high morbidity and mortality toll. While there is relative consensus regarding the bony part of the decompression, the role of dura opening and the optimal technique to perform it are under debate. Here we compared the commonly used augmented duraplasty technique to an understudied technique of dura fenestrations in a single center, prospective, non-controlled randomized study. The study included 23 patients who underwent decompressive craniectomy. The lowering of ICP was significant in both methods when compared to preoperative values and compared to pre-duraplasty values. The ICP was similar in various postoperative time points between both techniques. The rate of complications was lower when the dura was fenestrated - brain herniation was over five time less common, infection was more than five times rarer. Contusion expansion, meningitis and contralateral subdural collection were all lower in fenestrated dura cases than in wide dura opening. These results hold promise for a superior surgical approach in duraplasty for intracranial pressure reduction.