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Cannabis and the Gastrointestinal Tract.
J Pharm Pharm Sci
September 2021
In Vitro Drug Safety and Biotechnology and Department of Pharmacology and Toxicology, University of Toronto.
Unlabelled: Cannabis has been used for its medicinal purposes since ancient times. Its consumption leads to the activation of Cannabis receptors CB1 and CB2 that, through specific mechanisms can lead to modulation and progression of inflammation or repair. The novel findings are linked to the medical use of Cannabis in gastrointestinal (GI) system.
View Article and Find Full Text PDFCombination applicator for simultaneous heat and radiation.
Conf Proc IEEE Eng Med Biol Soc
June 2007
Dept. of Radiat. Oncology, California Univ., San Francisco, CA, USA.
We present the development of operator and patient friendly conformal applicators that can deliver moderate temperature hyperthermia simultaneously with radiation in superficial tissue overlying contoured anatomy. This applicator combines the uniform heating capabilities of large area conformal microwave array (CMA) flexible printed circuit board applicators with a patient interface (coupling bolus) that facilitates positioning of brachytherapy sources at a fixed distance (e.g.
View Article and Find Full Text PDFArachidonic acid regulation of steroid synthesis: new partners in the signaling pathway of steroidogenic hormones.
Endocr Res
November 2004
Department of Biochemistry, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina.
Although the role of arachidonic acid (AA) in trophic hormone-stimulated steroid production in various steroidogenic cells is well documented, the mechanism responsible for AA release remains unknown. We have previously shown evidence of an alternative pathway of AA generation in steroidogenic tissues. Our results are consistent with the hypothesis that, in steroidogenic cells, AA is released by the action of a mitochondrial acyl-CoA thioesterase (MTE-I).
View Article and Find Full Text PDFSynergism of aspirin and heparin with a low-frequency non-invasive ultrasound system for augmentation of in-vitro clot lysis.
J Thromb Thrombolysis
June 2003
Division of Cardiology, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
Background: Aspirin, glycoprotein IIb/IIIa inhibitors and heparin are routinely used in acute coronary syndromes. Previously we showed that there is synergism between ultrasound and heparin and tirofiban in augmenting blood clot disruption. However, there is a little data on a possible synergism of low-frequency ultrasound with aspirin for in-vitro clot dissolution, and especially on the combination of aspirin with heparin and/or glycoprotein IIb/IIIa inhibitors.
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