Anticoagulation of HeartMate 3 Left Ventricular Assist Device With Apixaban.

Ann Thorac Surg Short Rep

Division of Cardiac Surgery, Alberta Health Services, Edmonton, Alberta, Canada.

Published: March 2024

We report a case of a 56-year-old man requiring a HeartMate 3 after a myocardial infarction and limited recovery on a temporary ventricular assist device. Because of several gastrointestinal bleeding complications and nonadherence, his antithrombotic therapy was switched from warfarin and aspirin to apixaban 5 mg twice daily. We also determined several peak anti-factor Xa levels for ongoing monitoring. Direct oral anticoagulants may be an option for the prevention of pump thrombosis in patients who are unable to tolerate or refuse warfarin therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11708617PMC
http://dx.doi.org/10.1016/j.atssr.2023.09.014DOI Listing

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