Shiga Toxin: Emerging Producer Strains, Prophylactic Approaches, and Application in Cancer Therapy.

J Cancer Prev

Infectious Disease Research Center, Avicenna Institute of Clinical Sciences, Hamadan, IranAvicenna Health Research Institute, Hamadan University of Medical Sciences, Hamadan, Iran.

Published: December 2024

Shiga toxin-producing is the most prevalent bacterial strain responsible for Shiga toxin-related infections. While Shiga toxin is inherently toxic, it has potential therapeutic applications as a component of anticancer drugs. Despite its association with infections and harmful effects on human health, Shiga toxin is being explored as a viable element in drug delivery systems targeting cancer cells. The findings indicate that the production of mutated bacteria containing Shiga toxin is an effective preventive strategy for immunization against these toxins. Furthermore, the B subunit of Shiga toxin shows promise for imaging cancer cells, opening new paths for therapeutic interventions.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11706725PMC
http://dx.doi.org/10.15430/JCP.24.010DOI Listing

Publication Analysis

Top Keywords

shiga toxin
20
cancer cells
8
shiga
7
toxin emerging
4
emerging producer
4
producer strains
4
strains prophylactic
4
prophylactic approaches
4
approaches application
4
application cancer
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!