Pleomorphic carcinoma of the lung is highly malignant and occurs mostly in the upper lobes of smokers; however, no reports exist of new occurrences from the resection margins of the previous ground-glass opacities. In our case, a 73-year-old man underwent an initial partial resection of the left upper lung for ground-glass opacities, with progressive thickening of the resection margin during the following 10 months. Radical resection was performed, resulting in the diagnosis of a newly arising pleomorphic carcinoma from previously resected margins.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11708683PMC
http://dx.doi.org/10.1016/j.atssr.2023.12.025DOI Listing

Publication Analysis

Top Keywords

pleomorphic carcinoma
12
ground-glass opacities
12
resection margins
8
resection
5
carcinoma arising
4
arising previous
4
previous resection
4
margins ground-glass
4
opacities pleomorphic
4
carcinoma lung
4

Similar Publications

Myoepithelial carcinoma (MC) is a rare salivary gland malignancy that usually affects people over the age of 50. The incidence is similar in both men and women. MC might develop de novo or within a pre-existing benign myoepithelioma or pleomorphic adenoma.

View Article and Find Full Text PDF

Background: Hepatocellular carcinoma (HCC) encompasses rare variants like chromophobe hepatocellular carcinoma (CHCC) characterized by distinct histological features and molecular profiles.

Case Report: A 56-year-old male with chronic hepatitis C, presenting pain in the right hypochondrium. Imaging revealed a solitary liver lesion, subsequently resected and histologically diagnosed as HCC.

View Article and Find Full Text PDF

Carcinoma ex pleomorphic adenomas are rare malignant tumors of the salivary glands, primarily seen in older adults. They originate from benign pleomorphic adenomas, are aggressive, and have poorer prognosis. This case documents an unusual presentation of a massive carcinoma ex pleomorphic adenoma.

View Article and Find Full Text PDF

Pleomorphic adenoma (PA), the most prevalent salivary gland tumor, exhibits a diverse histological spectrum characterized by epithelial, myoepithelial, and mesenchymal patterns, and secretory products. However, a subset of PAs presents microscopic features suggestive of malignancy, leading to challenging and potentially significant diagnostic pitfalls. A comprehensive retrospective analysis was conducted on the Salivary Gland Tumor Registry, compiled by the authors.

View Article and Find Full Text PDF

Background: Aurora kinase A (AurkA) plays a vital role in mitosis and is therefore critical in tumors development and progression. There are a few studies on AurkA expression in salivary gland tumors. The aim of the present study was to evaluate the expression pattern of AurkA in the most common benign and malignant salivary gland tumors by immunohistochemistry.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!