Thymic carcinoma, a rare aggressive tumor, necessitates multidisciplinary approaches for optimal prognosis. The role of surgical interventions in stage IVb thymic carcinoma, as classified by the TNM and Masaoka-Koga staging systems, remains controversial; although some patients present with resectable disease, others do not. We report a case with supraclavicular metastasis and sternal invasion. Preoperative chemoradiotherapy, followed by extended thymectomy and thorough lymph node dissection, resulted in more than a decade of postoperative recurrence-free survival. Complete resection, including metastases, is essential for achieving optimal outcomes, underscoring the need for extensive lymph node dissection. Aggressive surgical procedure is recommended for suitably selected patients.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11708622 | PMC |
http://dx.doi.org/10.1016/j.atssr.2024.01.002 | DOI Listing |
Ann Thorac Surg Short Rep
December 2023
Department of Thoracic Surgery, Japanese Red Cross Osaka Hospital, Osaka, Japan.
A 58-year-old woman underwent an extended thymectomy and left upper lobectomy subsequent to induction chemoradiotherapy for advanced thymic carcinoma. The pathologic stage of the tumor was ypT0 N0 M0 stage 0. Six months after surgery, she presented with edema in her left arm and left breast.
View Article and Find Full Text PDFAnn Thorac Surg Short Rep
December 2024
Division of Cardiothoracic Surgery, University of California, San Diego, California.
Thymomas have been associated with the generation of paraneoplastic autoantibodies to neurogenic epitopes, collapsin-response-mediator protein-5 receptor (CRMP-5) and alpha-amino-3-hydroxyl-5methyl-4isoxazolepropionic acid receptor (AMPAR), in patients with acute viral infection. We report a patient with thymoma and myasthenia gravis, with SARS-CoV-2 infection, who became comatose secondary to autoimmune encephalitis. Plasmapheresis, high-dose steroids, pyridostigmine, eculizumab, and rituximab did not restore neurologic function.
View Article and Find Full Text PDFAnn Thorac Surg Short Rep
December 2024
Interventional Radiology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Background: The study evaluated the safety and adequacy of percutaneous transsternal anterior mediastinal core biopsy.
Methods: All percutaneous computed tomography-guided transsternal mediastinal 18-gauge core biopsies performed at 2 academic centers were retrospectively reviewed. Procedural, clinical, and pathology data were recorded.
Ann Thorac Surg Short Rep
September 2024
Department of General Thoracic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Stiff person syndrome (SPS) is a neurologic disorder, some cases of which are associated with malignant disease. Here, we report a case of thymoma-associated SPS that was successfully treated with surgical resection. A 57-year-old man with progressive muscle stiffness and weakness was diagnosed with thymoma-related SPS.
View Article and Find Full Text PDFAnn Thorac Surg Short Rep
June 2024
Division of General Thoracic Surgery, Department of Surgery, Shiga University of Medical Science, Otsu, Shiga, Japan.
Thymic carcinoma, a rare aggressive tumor, necessitates multidisciplinary approaches for optimal prognosis. The role of surgical interventions in stage IVb thymic carcinoma, as classified by the TNM and Masaoka-Koga staging systems, remains controversial; although some patients present with resectable disease, others do not. We report a case with supraclavicular metastasis and sternal invasion.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!