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Radar versus optical: The impact of cloud cover when mapping seasonal surface water for health applications in monsoon-affected India.
PLoS One
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UK Centre for Ecology and Hydrology, Crowmarsh Gifford, Wallingford, United Kingdom.
Surface water plays a vital role in the spread of infectious diseases. Information on the spatial and temporal dynamics of surface water availability is thus critical to understanding, monitoring and forecasting disease outbreaks. Before the launch of Sentinel-1 Synthetic Aperture Radar (SAR) missions, surface water availability has been captured at various spatial scales through approaches based on optical remote sensing data.
View Article and Find Full Text PDFApoptosis in Cancer Biology and Therapy.
Annu Rev Pathol
January 2025
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; email:
Since its inception, the study of apoptosis has been intricately linked to the field of cancer. The term apoptosis was coined more than five decades ago following its identification in both healthy tissues and malignant neoplasms. The subsequent elucidation of its molecular mechanisms has significantly enhanced our understanding of how cancer cells hijack physiological processes to evade cell death.
View Article and Find Full Text PDFRoles of Cellular Neighborhoods in Hepatocellular Carcinoma Pathogenesis.
Annu Rev Pathol
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Liver Cancer Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.
The development of hepatocellular carcinoma (HCC) involves an intricate interplay among various cell types within the liver. Unraveling the orchestration of these cells, particularly in the context of various etiologies, may hold the key to deciphering the underlying mechanisms of this complex disease. The advancement of single-cell and spatial technologies has revolutionized our ability to determine cellular neighborhoods and understand their crucial roles in disease pathogenesis.
View Article and Find Full Text PDFUnraveling Mechanisms of Genetic Risks in Metabolic Dysfunction-Associated Steatotic Liver Diseases: A Pathway to Precision Medicine.
Annu Rev Pathol
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MASLD Research Center, Division of Gastroenterology, University of California at San Diego, La Jolla, California, USA; email:
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing global health problem, affecting ∼1 billion people. This condition is well established to have a heritable component with strong familial clustering. With the extraordinary breakthroughs in genetic research techniques coupled with their application to large-scale biobanks, the field of genetics in MASLD has expanded rapidly.
View Article and Find Full Text PDFBiofield Therapies Clinical Research Landscape: A Scoping Review and Interactive Evidence Map.
J Integr Complement Med
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Research Consultant to Subtle Energy Funders Collective, Warwick, New York, USA.
Biofield Therapies, with a historical lineage spanning millennia and continuing relevance in contemporary practices, have been used to address various health conditions and promote wellbeing. The scientific study and adoption of these therapies have been hindered by cultural challenges and institutional barriers. In addition, the current research landscape for Biofield Therapies is insufficiently documented.
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