The importance of central hemodynamic metrics such as Central blood pressure (CBP), which directly measure the pressure exerted by the cardiac muscle on the major arteries, offering a more direct assessment of cardiovascular workload compared to brachial blood pressure (bBP), which measures pressure against the walls of peripheral arteries. This review consolidates findings that evaluate the correlation between CBP and key markers of aortovascular disease. The growth of thoracic aortic aneurysm (TAA) is a significant component of aortovascular assessment. CBP correlates more precisely with arterial stiffness (AS), TAA growth, and cardiovascular diseases, providing a more reliable forecast of aortovascular diseases, adverse cardiovascular events (CVE), and organ damage than bBP. Integrating CBP into routine clinical practice could enhance aortovascular assessments and therapeutic strategies compared to bBP, especially by gaining a deeper understanding of aortic wave dynamics, which could fundamentally change aortovascular diagnostics and treatment. It is recommended to incorporate CBP into aortovascular and cardiovascular risk management. Further research is needed to confirm these aspects and to explore the practical implications of CBP in clinical settings.
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http://dx.doi.org/10.1016/j.cpcardiol.2025.102981 | DOI Listing |
Circ Res
January 2025
Department of Physiology, Institute of Functional Genomics and Research Institute of Medical Science, Konkuk University School of Medicine, Chungju, Republic of Korea (H.L., S.P., J.R.A., M.S.S., H.J.N., B.K., Y.M.B.).
J Hypertens
December 2024
Department of Ultrasound Medicine, Tangdu Hospital, Air Force Medical University.
Background: The arterial stiffening is attributed to the intrinsic structural stiffening and/or load-dependent stiffening by increased blood pressure (BP). The respective lifetime alterations and major determinants of the two components with normal aging are not clear.
Methods: A total of 3053 healthy adults (1922 women) aged 18-79 years were enrolled.
J Hypertens
December 2024
University/British Heart Foundation Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, Scotland, UK.
Introduction: Hypertension is the leading preventable cause of cardiovascular morbidity and mortality globally, with a disproportionate impact on low-income and middle-income countries like Sri Lanka. Effective blood pressure (BP) control improves outcomes in patients with hypertension. This study aimed to assess the prevalence of uncontrolled hypertension, and its correlates among Sri Lankan patients with hypertension in clinic settings.
View Article and Find Full Text PDFJCEM Case Rep
January 2025
Division of Diabetology and Metabolism, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Shinjuku-ku, Tokyo 162-8666, Japan.
A 37-year-old man presented with symptoms of polyuria and weight loss over the past year. Initial laboratory examination showed elevated blood glucose level (468 mg/dL [25.9 mmol/L]; normal reference range [RR], 75-109 mg/dL [4.
View Article and Find Full Text PDFJ Family Med Prim Care
December 2024
Department of Community Medicine, Smt. B.K. Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara, Gujarat, India.
Introduction: Accredited Social Health Activists (ASHA) play a pivotal role as village-level functionaries under the National Health Mission, driving community transformation, facilitating health planning, and ensuring access to healthcare services.
Objectives: To assess the physical health status of ASHA workers and to investigate the prevalence of morbidities among ASHA workers.
Material And Methods: This is a cross-sectional study, conducted in Vadodara's east zone, and involves 123 ASHA workers.
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