Bugs take the sting out.

Cell Host Microbe

Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address:

Published: January 2025

Jiang et al. investigate the role of the microbiota in postherpetic neuralgia (PHN), a chronic pain condition resulting from varicella-zoster virus reactivation. They identify microbiome alterations in PHN patients, linking microbes and pain sensitivity. The researchers identify butyrate-producing Roseburia intestinalis as a mediator of pain sensitivity along the "gut-brain axis."

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http://dx.doi.org/10.1016/j.chom.2024.12.008DOI Listing

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