Biological sex matters in brain aging.

Neuron

Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA; Molecular and Computational Biology Department, USC Dornsife College of Letters, Arts and Sciences, Los Angeles, CA, USA; Biochemistry and Molecular Medicine Department, USC Keck School of Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA; USC Stem Cell Initiative, Los Angeles, CA, USA. Electronic address:

Published: January 2025

Every cell in the body has a biological sex. The expansion of aging research to investigate female- and male-specific biology heralds a major advance for human health. Unraveling and harnessing mechanistic etiologies of sex differences may reveal new diagnostics and therapeutics for the aging brain.

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http://dx.doi.org/10.1016/j.neuron.2024.12.005DOI Listing

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