The design of the prosthetic replacement of the ocular surface ecosystem (PROSE) device allows it to serve as a novel drug delivery system. In this article, we describe the off-label administration of amphotericin B and cenegermin by instillation in the PROSE device reservoir for the treatment of Candida keratitis in the setting of a persistent epithelial defect.
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An open source ultrasonic flowmeter for monitoring the input/output flow rates of wastewater treatment plants.
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INRAE - French National Research Institute for Agriculture, Food and Environment, REVERSAAL Research Unit, 5 rue de la Doua, CS 20244, 69625 Villeurbanne Cedex, France.
Sensors play an important role in both the continuous monitoring and intermittent analyses, which are essential for the study of wastewater treatment plant management and conducting related research. Given the significant environmental impact of the issues involved, accurate measurement of the volume of water flowing into and out of treatment plants is a key parameter for plant management, ecotoxicological studies and academic research programs. Traditionally, flow measurements have been based on calibrated weirs or venturi flumes, using water level measurements for conversion into flow, according to established relationships.
View Article and Find Full Text PDFDrug Delivery in PROSE Device as Alternative to Frequent Drop Administration in Severe Ocular Surface Disease.
Eye Contact Lens
December 2024
Department of Ophthalmology, Massachusetts Eye & Ear, Harvard University, Boston, MA.
The design of the prosthetic replacement of the ocular surface ecosystem (PROSE) device allows it to serve as a novel drug delivery system. In this article, we describe the off-label administration of amphotericin B and cenegermin by instillation in the PROSE device reservoir for the treatment of Candida keratitis in the setting of a persistent epithelial defect.
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Clin Ophthalmol
November 2024
Department of Ophthalmology, BostonSight, Needham, MA, USA.
Purpose: To evaluate the tolerability of utilizing Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) as a drug delivery device for preservative-free cyclosporine 0.05% for the treatment of dry eye disease.
Patients And Methods: Fourteen current daily PROSE wearers were enrolled, with four screen failures and one subject that did not complete the study protocol due to burning and stinging.
Developing and Validating the Health Literacy Scale for Migrant Workers: Instrument Development and Validation Study.
JMIR Public Health Surveill
November 2024
School of Nursing, Johns Hopkins University, 525 N Wolfe St, Baltimore, MD, 21205-2110, United States, 1 4106142669, 1 4432870547.
Article Synopsis
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Sustained descemetocele management with Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment.
Am J Ophthalmol Case Rep
December 2024
Department of Ophthalmology, USC Roski Eye Institute, University of Southern California Keck School of Medicine, 1450 San Pablo Street, 4th Floor, Los Angeles, CA, 90033, USA.
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